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Metabolic changes in schizophrenia and human brain evolution
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Date
2008-01-01
Author
Khaitovich, Philipp
Lockstone, Helen E.
Wayland, Matthew T.
Tsang, Tsz M.
Jayatilaka, Samantha D.
Guo, Arfu J.
Zhou, Jie
Somel, Mehmet
Harris, Laura W.
Holmes, Elaine
Paeaebo, Svante
Bahn, Sabine
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Background: Despite decades of research, the molecular changes responsible for the evolution of human cognitive abilities remain unknown. Comparative evolutionary studies provide detailed information about DNA sequence and mRNA expression differences between humans and other primates but, in the absence of other information, it has proved very difficult to identify molecular pathways relevant to human cognition.
Subject Keywords
Magnetic-resonance-spectroscopy
,
Formal thought-disorder
,
Gene-expression
,
Human genome
,
Positive selection
,
Nmr-Spectroscopy
,
Homo-sapiens
,
Cortex
,
Proton
,
Dysfunction
URI
https://hdl.handle.net/11511/38395
Journal
GENOME BIOLOGY
DOI
https://doi.org/10.1186/gb-2008-9-8-r124
Collections
Department of Biology, Article
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P. Khaitovich et al., “Metabolic changes in schizophrenia and human brain evolution,”
GENOME BIOLOGY
, pp. 0–0, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/38395.