Metabolic changes in schizophrenia and human brain evolution

Khaitovich, Philipp
Lockstone, Helen E.
Wayland, Matthew T.
Tsang, Tsz M.
Jayatilaka, Samantha D.
Guo, Arfu J.
Zhou, Jie
Somel, Mehmet
Harris, Laura W.
Holmes, Elaine
Paeaebo, Svante
Bahn, Sabine
Background: Despite decades of research, the molecular changes responsible for the evolution of human cognitive abilities remain unknown. Comparative evolutionary studies provide detailed information about DNA sequence and mRNA expression differences between humans and other primates but, in the absence of other information, it has proved very difficult to identify molecular pathways relevant to human cognition.

Citation Formats
P. Khaitovich et al. , “Metabolic changes in schizophrenia and human brain evolution,” GENOME BIOLOGY, vol. 9, no. 8, pp. 0–0, 2008, Accessed: 00, 2020. [Online]. Available: