Formation and Characterization of Green Tea Extract Loaded Liposomes

Date

2017-02-01

Author

DAG, Damla
Öztop, Halil Mecit

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

112
views

0
downloads

Green tea extract was encapsulated into liposomes to enhance bioavailability and stability of catechins by protecting their functional properties simultaneously. Encapsulation was achieved by dispersing 1% (w/v) soy lecithin through high pressure homogenization (microfluidization) and ultrasonication. Effects of homogenization type and pH of the dispersing medium on the physical properties and stability of the liposomes during 1-mo storage period were investigated. Mean particle size, total phenolic content by Folin-Ciocalteu method and antioxidant activity by 2-diphenyl-1-picrylhydrazyl radical scavenging and ferric reducing-antioxidant power methods, and transmission electron microscopy (TEM) experiments were conducted for characterization. Green tea extract loaded liposomes prepared by microfluidization in distilled water were determined as the most stable system which demostrated no significant difference (P > 0.05) on mean particle size, total phenolic content, and antioxidant activity between the first and final day of 1-mo storage time. Additionally, uniform size and shape in TEM images supported the results.

Subject Keywords

Encapsulation, Green tea, Liposome, Microfluidization, Ultrasonication

URI

https://hdl.handle.net/11511/38501

Journal

JOURNAL OF FOOD SCIENCE

DOI

https://doi.org/10.1111/1750-3841.13615

Collections

Department of Food Engineering, Article

Suggestions

OpenMETU
Core

Characterization of Green Tea Extract Loaded Liposomes Dag, Damla; Öztop, Halil Mecit (2016-08-25) Green tea extract was encapsulated into liposomes to enhance bioavailability and stability of catechins that are the main bioactive compounds and to protect the functional properties of green tea. Green tea extract (w/w 0.1%) was encapsulated by dispersing 1 % (w/w) soy lecithin through high pressure homogenization and ultrasonication techniques. Effect of homogenization type and pH of the dispersing medium was investigated. Mean particle size, total phenolic content by FolinCiocalteu Method and antioxidant...
Effect of extrusion on bioactive compounds found in artichoke leaf powder and on their in vitro bioaccessibilities Güven, Özge; Şensoy, İlkay; Şenyuva, Hamide Z.; Department of Food Engineering (2016) The functional properties of extruded products can be enhanced by addition of herbal ingredients. In this study, artichoke leaf powder (ALP) was added to extrudates, at 3%, 6% and 9% concentrations, to increase amount of bioactive nutrients. Aim of the study was to investigate the effect of extrusion on functional components and in vitro bioaccessibility of selected phenolic compounds. Extrusion feed flow rate was 55 ± 1 g/min, screw speed was 250 rpm and barrel temperature zones were set at 80°C, 90°C, 130...
Green synthesis of iron nanoparticles and their application as a Fenton-like catalyst for the degradation of aqueous cationic and anionic dyes Shahwan, T.; Abu Sirriah, S.; Nairat, M.; Boyacı, Ezel; Eroglu, A. E.; Scott, T. B.; Hallam, K. R. (2011-08-01) Iron nanoparticles were produced using extracts of green tea leaves (GT-Fe NPs). The materials were characterized using TEM. SEM/EDX, XPS, XRD, and FTIR techniques and were shown to contain mainly iron oxide and iron oxohydroxide. The obtained nanoparticles were then utilized as a Fenton-like catalyst for decolorization of aqueous solutions containing methylene blue (MB) and methyl orange (MO) dyes. The related experiments investigated the removal kinetics and the effect of concentration for both MB and MO....
Synthesis and characterization of conducting copolymers of poly(vinyl alcohol) with thiophene side-groups and pyrrole Sahmetlioglu, E; Yuruk, H; Toppare, Levent Kamil; Cianga, I; Yagci, Y (2004-12-01) Graft copolymers of poly(vinyl alcohol) with thiophene side-groups and pyrrole were synthesized by electrochemical polymerization methods. Poly(vinyl alcohol) with thiophene side-groups (PVATh) was obtained from the reaction between poly(vinyl alcohol) (PVA) and thiophene-3-acetic acid. The syntheses of copolymers Of PVATh and pyrrole were achieved electrochemically by using three different supporting electrolytes, p-toluene sulfonic acid (PTSA), sodium dodecyl sulfate (SDS) and tetrabutylammonium tetrafluo...
Inclusion of celecoxib in the SBA-15 mesoporous silica: drug loading and release property Eren, Zeynep Seda; Yılmaz, Ayşen; Department of Chemistry (2016) Mesoporous silica particles have been used to enhance the loading capacity of drugs into the support, increase the solubility of drug and control drug release. In this study, poorly water-soluble, nonsteroidal anti-inflammatory drug with relatively low bioavailability Celecoxib, was used as a model drug in order to determine the drug loading and release properties of silica particles. In order to synthesize SBA15 particles, hydrothermal synthesis method was used, SBA-15 samples were functionalized by post-g...

Citation Formats

D. DAG and H. M. Öztop, “Formation and Characterization of Green Tea Extract Loaded Liposomes,” JOURNAL OF FOOD SCIENCE, pp. 463–470, 2017, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/38501.