Characterization of Green Tea Extract Loaded Liposomes

2016-08-25
Dag, Damla
Öztop, Halil Mecit
Show full item record
145
views
0
downloads
Green tea extract was encapsulated into liposomes to enhance bioavailability and stability of catechins that are the main bioactive compounds and to protect the functional properties of green tea. Green tea extract (w/w 0.1%) was encapsulated by dispersing 1 % (w/w) soy lecithin through high pressure homogenization and ultrasonication techniques. Effect of homogenization type and pH of the dispersing medium was investigated. Mean particle size, total phenolic content by FolinCiocalteu Method and antioxidant activity by DPPH Radical Scavenging method and Ferric Reducing-Antioxidant Power (FRAP) method, and transmission electron microscopy (TEM) experiments were conducted for characterizing liposomes. Change in the mean particle size of liposomes between first day and one month storage time was not found significant (p > 0.05) for the liposomes prepared by distilled water (pH 6.5) by microfluidizer and ultrasonication while there was significant difference on the mean particle sizes of liposomes (p ≤ 0.05) for the samples prepared in acetate buffer (pH:3.8) for the 2 homogenization techniques. Difference in antioxidant activity measured by DPPH Radical Scavenging method between first and final day of one month storage time of liposomes was not significant (p > 0.05) for the liposomes prepared by microfluidizer in distilled water and acetate buffer while significant difference (p ≤ 0.05) was found in antioxidant activity for samples prepared by ultrasonication in both medium.
https://hdl.handle.net/11511/71905
IUFoST 2016 - 18th World Congress of Food Science and Technology (21 - 25 Ağustos 2016)
Department of Food Engineering, Conference / Seminar

Suggestions

Formation and Characterization of Green Tea Extract Loaded Liposomes
DAG, Damla; Öztop, Halil Mecit (2017-02-01)
Green tea extract was encapsulated into liposomes to enhance bioavailability and stability of catechins by protecting their functional properties simultaneously. Encapsulation was achieved by dispersing 1% (w/v) soy lecithin through high pressure homogenization (microfluidization) and ultrasonication. Effects of homogenization type and pH of the dispersing medium on the physical properties and stability of the liposomes during 1-mo storage period were investigated. Mean particle size, total phenolic content...
Determination of phenolic and flavoniod compounds in rehum ribes
Fazeli, Sepideh; Çoruh, Nursen; Department of Biochemistry (2016)
This study involves the investigation of antioxidant phenolic and flavonoid compounds in Rheum ribes L. There is a continuous mounting pressure, in the scientific world, to discover new and potent antioxidants, to combat the free radicals. Among the antioxidant compounds, the phenolics and flavonoids comprise the largest class, and thus hold an important place in biochemical studies. Rheum ribes belong to the family of Polygonaceae in the genus Rheum, which is consumed as a medicinal plant. Since this plant...
Investigation of antioxidant activities of fruit juices and herbal teas and their antimicrobial effects on proteus mirabilis
Kümbet, Yeşim; Çoruh, Nursen; Sağdıçoğlu Celep, A. Gülçin; Department of Biochemistry (2010)
Herbal teas and fruit juices used in our regular diet may have importance in the protective treatment of some infectious diseases. In this study, selected dietary beverages were investigated for their antioxidant capacities and antimicrobial activities against Proteus mirabilis, a well known bacteria in urinary tract infections. Herbal teas; sage (Salvia fruticosa Mill), anise (Pimpinella anisum L.), rosehip (Rosa canina L.), camomile (Anthemis arvensis L.) and fruit juices; grape (Vitis vinifera L.), orang...
Determination of phenolic compounds in aconitum cochleare woroschin
Rafiq, Azra; Çoruh, Nursen; Department of Biochemistry (2015)
This study involves the investigation of antioxidant phenolic compounds in Aconitum cochleare. There is a continuous mounting pressure, in the scientific world, to discover new and potent antioxidants, to combat the free radicals. Among the antioxidant compounds, the phenolics comprise the largest class, and thus hold an important place in biochemical studies. Phenolics are abundantly present in some plant families as secondary metabolites and Ranunculaceae is one of those families that contain alkaloids an...
Evaluation and discrimination of simvastatin-induced structural alterations in proteins of different rat tissues by FTIR spectroscopy and neural network analysis
Garip, Sebnem; Yapici, Engin; Ozek, Nihal Simsek; Severcan, Mete; Severcan, Feride (Royal Society of Chemistry (RSC), 2010-01-01)
Statins are commonly used to control hypercholesterolemia and to prevent cardiovascular diseases. Among the statins, Simvastatin is one of the most frequently prescribed statins because of its efficacy in reducing LDL lipoprotein cholesterol levels, its tolerability, and its reduction of cardiovascular risk and mortality. Conflicting results have been reported with regard to benefits (pleiotropic effects) as well as risks (adverse effects) of simvastatin on different soft and hard tissues. In the current st...
Citation Formats
D. Dag and H. M. Öztop, “Characterization of Green Tea Extract Loaded Liposomes,” presented at the IUFoST 2016 - 18th World Congress of Food Science and Technology (21 - 25 Ağustos 2016), Dublin, Ireland, 2016, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/71905.
METU IIS - Integrated Information Service open@metu.edu.tr