Resolution of (±)-2-substituted norbornadiene and hexachloronorbornadiene derivatives using CCL and PLE

Date

2001-09-13

Author

Tanyeli, Cihangir
Akhmedov, Idris Mecidolu

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(+/-)-2-Hydroxymethylbicyclo[2.2.1]hepta-2,5-diene. (+/-)-2-acetoxymethylbicyclo[2.2.1]hepta-2,5-diene and their hexachlorinated derivatives were resolved via CCL- and PLE-catalysed hydrolysis to afford enantiomerically enriched products with e.e.s of 61-93%. The absolute configurations were determined by transforming 2-hydroxymethylbicyclo[2.2.1]hepta-2,5-diene into the 2-formylbicyclo[2.2.1]hepta-2,5-diene with known absolute configuration.

Subject Keywords

Ketones

URI

https://hdl.handle.net/11511/40101

Journal

Tetrahedron Asymmetry

DOI

https://doi.org/10.1016/s0957-4166(01)00413-x

Collections

Department of Chemistry, Article

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Citation Formats

C. Tanyeli and I. M. Akhmedov, “Resolution of (±)-2-substituted norbornadiene and hexachloronorbornadiene derivatives using CCL and PLE,” Tetrahedron Asymmetry, pp. 2305–2308, 2001, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/40101.