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Fam-Ti catalyzed enantioselective alkynylation of aldehydes
Date
2007-08-16
Author
KOYUNCU, Hasan
Doğan, Özdemir
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Ferrocenyl-substituted aziridinylmethanol (Fam-1) has been used as a chiral catalyst with titanium for enantioselective alkynylation of aromatic, heteroaromatic, aliphatic, and alpha,beta-unsaturated aldehydes to give the corresponding propargylic alcohols in up to 96% yield and 96% ee. The ligand can be prepared easily and recycled.
Subject Keywords
Physical and Theoretical Chemistry
,
Organic Chemistry
,
Biochemistry
URI
https://hdl.handle.net/11511/40718
Journal
ORGANIC LETTERS
DOI
https://doi.org/10.1021/ol701535y
Collections
Department of Chemistry, Article
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H. KOYUNCU and Ö. Doğan, “Fam-Ti catalyzed enantioselective alkynylation of aldehydes,”
ORGANIC LETTERS
, pp. 3477–3479, 2007, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/40718.