Fam-Ti catalyzed enantioselective alkynylation of aldehydes

Date

2007-08-16

Author

KOYUNCU, Hasan
Doğan, Özdemir

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Ferrocenyl-substituted aziridinylmethanol (Fam-1) has been used as a chiral catalyst with titanium for enantioselective alkynylation of aromatic, heteroaromatic, aliphatic, and alpha,beta-unsaturated aldehydes to give the corresponding propargylic alcohols in up to 96% yield and 96% ee. The ligand can be prepared easily and recycled.

Subject Keywords

Physical and Theoretical Chemistry, Organic Chemistry, Biochemistry

URI

https://hdl.handle.net/11511/40718

Journal

ORGANIC LETTERS

DOI

https://doi.org/10.1021/ol701535y

Collections

Department of Chemistry, Article

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Citation Formats

H. KOYUNCU and Ö. Doğan, “Fam-Ti catalyzed enantioselective alkynylation of aldehydes,” ORGANIC LETTERS, pp. 3477–3479, 2007, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/40718.