Patient classification considering the risk of restenosis after coronary stent placement

Date

2019-10-01

Author

Sahin, Halenur
Duran, Serhan
Yakici, Ertan
Sahin, Mahmut

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

59
views

0
downloads

Aging and some lifestyle habits cause plaque accumulation in the blood vessels of the heart and this causes narrowing of the arteries. Stents are tiny wire mesh tubes which are used in balloon angioplasty to keep the vessels open. However, the stented vessel has a risk of re-narrowing due to the recovery response of the stented vessel segment and this is called in-stent-restenosis. The objective of this study is classifying patients according to their risks of restenosis. For this purpose, first a utilites additives discriminates model called parametrized classification model is developed, then to improve the classification performance of this model, a non-dominated sorting based multi-objective evolutionary algorithm (NSGA-II) is implemented. Finally, computational experiments are conducted with real life data to demonstrate the efficiency of proposed methods.

Subject Keywords

Management Science and Operations Research, Computer Networks and Communications, Software, Control and Optimization, Artificial Intelligence, Information Systems

URI

https://hdl.handle.net/11511/41885

Journal

JOURNAL OF HEURISTICS

DOI

https://doi.org/10.1007/s10732-018-9394-9

Collections

Department of Industrial Engineering, Article

Suggestions

OpenMETU
Core

Large eddy simulation of pressure fluctuations inside stenosed blood vessels towards noninvasive diagnosis of atherosclerosis Özden, Kamil; Sert, Cüneyt; Yazıcıoğlu, Yiğit; Department of Mechanical Engineering (2018) Atherosclerosis is a cardiovascular disease, in which plaque builds up inside a blood vessel, narrowing it down and forming a stenosis that adversely affects the flow. Because of the stenosis, turbulent flow occurs at the post-stenotic region, which causespressure fluctuations on the vessel wall. The resulting murmurpropogates through the surrounding tissue and reaches the skin surface. These sounds emitted from the stenosed vessels are evaluated as a sign of stenosis. In this study, large eddy simulations ...
Large Eddy Simulation of Blood Flow Inside Vessels for Acoustic Diagnosis of Atherosclerosis Sert, Cüneyt; Yazıcıoğlu, Yiğit (2018-10-20) Atherosclerosis is a cardiovascular disease, in which plaque builds up inside a blood vessel, narrowing it down and forming a stenosis that adversely affects flow. Because of the constriction, turbulent flow occurs at the post-stenotic region, which leads pressure fluctuations on the vessel wall. The murmur caused by this interaction propagates through the surrounding tissue and reaches the skin surface. These sounds emitted from the stenosed vessels are evaluated as a sign of stenosis. In this study, large...
Human serum arylesterase and glutathione s-transferase activities in patients with ischemic stroke compared to healthy controls Türkanoğlu, Aysun; Adalı, Orhan; Department of Biochemistry (2007) Stroke is an important public health problem and the third leading cause of death after coronary heart diesase and all cancers in all over the world. Free radicals and oxidative stress play important role in the pathogenesis of several diseases including atherosclerosis, stroke, cancer, neurodegenerative diseases such as Alzheimer's dementia. The activity of paraoxonase (PON1) aganist phenylacetate is known as arylesterase (ARE). Paraoxonase is an esterase associated with high-density lipoprotein (HDL) and ...
Early alterations in myocardia and vessels of the diabetic rat heart: an FTIR microspectroscopic study Toyran, Neslihan; Lasch, Peter; Naumann, Dieter; Turan, Belma; Severcan, Feride (2006-08-01) Diabetes mellitus is associated with a high incidence and poor prognosis of cardiovascular disease. The aim of the present study was to examine the effect of relatively short-term (5 weeks) Type I diabetes on the left ventricle, the right ventricle and the vessel (vein) on the left ventricle of the myocardium, at molecular level by FTIR (Fourier-transform infrared) microspectroscopy. The rats were categorized into two groups: control group (for the left ventricle myocardium, n = 8; for the right ventricle m...
Assessment of the impacts of hyperlipidemia on brain and modulation of perk pathway against hyperlipidemia- induced synaptic impairment on hippocampus Aşkın, Bilge; Yanık, Tülay.; Department of Molecular Biology and Genetics (2019) Hyperlipidemia is characterized by elevated total cholesterol levels in the circulation, and it is often associated with co-occurrence of neuronal dysfunction and subsequent neurodegeneration. Hyperlipidemia-induced inflammation, synaptic damage and neuronal loss in hippocampus as well as in other regions of the brain consequently leads to cognitive decline. Due to its role in protein translation and cell fate determination, PKR-like endoplasmic reticulum kinase (PERK) arm of the Endoplasmic Reticulum (ER) ...

Citation Formats

H. Sahin, S. Duran, E. Yakici, and M. Sahin, “Patient classification considering the risk of restenosis after coronary stent placement,” JOURNAL OF HEURISTICS, pp. 703–729, 2019, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/41885.