Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings

Date

2014-07-01

Author

Gungor, Bilgi
Yagci, Fuat Cem
GÜRSEL, İHSAN
Gürsel, Mayda

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Type I interferon inducers may potentially be engineered to function as antiviral and anticancer agents, or alternatively, vaccine adjuvants, all of which may have clinical applications. We recently described a simple strategy to convert a Toll-like receptor 9 (TLR9) agonist devoid of interferon alpha (IFN alpha) stimulating activity into a robust Type I interferon inducer with potent vaccine adjuvant activity.

Subject Keywords

CpG ODN, Type I interferon, Vaccine adjuvant

URI

https://hdl.handle.net/11511/42937

Collections

Department of Biology, Article