Nanosize hydroxyapatite: doping with various ions

Date

2011-07-01

Author

Evis, Zafer

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Natural crystal sizes of bone minerals are present in the nanoscale regime (specifically less than 100 nm in at least one direction). Therefore, research on the synthesis and characterisation of nanosize hydroxyapatite has gained significant importance in numerous biomedical applications. This is because currently used pure micrometre sized hydroxyapatite has poor mechanical properties, which limits it use in non-load bearing applications. For these reasons, various ions could be easily substituted into nanostructured hydroxyapatite to alter its biocompatibility, sinterability and mechanical properties. In this study, the synthesis methods, biocompatibility, physical, microstructural and nanostructural characteristics of nanocrystalline hydroxyapatite are reviewed. Compared to pure micrometre structured hydroxyapatite, numerous properties (most notably, biocompatibility properties pertinent for orthopedic applications) are improved for nanostructured hydroxyapatite doped with various ions. Such studies demonstrated that the mechanical properties and phase stability of nanohydroxyapatite doped with various ions after sintering at high temperatures should be investigated in more detail.

Subject Keywords

Bioceramics, Chemical synthesis, X-ray diffraction, Mechanical properties

URI

https://hdl.handle.net/11511/45608

Journal

ADVANCES IN APPLIED CERAMICS

DOI

https://doi.org/10.1179/1743676110y.0000000005

Collections

Department of Engineering Sciences, Article

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Citation Formats

Z. Evis, “Nanosize hydroxyapatite: doping with various ions,” ADVANCES IN APPLIED CERAMICS, pp. 311–320, 2011, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/45608.