Anterior Mitral Leaflet Curvature During the Cardiac Cycle in the Normal Ovine Heart

Kvitting, JPE
Bothe, Wolfgang
Göktepe, Serdar
Rausch, Manuel
Swanson, Julia
Kuhl, Ellen
Ingels, Neil
Miller, Craig
Background-The dynamic changes of anterior mitral leaflet (AML) curvature are of primary importance for optimal left ventricular filling and emptying but are incompletely characterized.


How do annuloplasty rings affect mitral leaflet dynamic motion?
Bothe, Wolfgang; Kvitting, JPE; Swanson, Julia; Göktepe, Serdar; Vo, Kathy; Ingels, Neil; Miller, Craig (Oxford University Press (OUP), 2010-09-01)
Objectives: To define the effects of annuloplasty rings (ARs) on the dynamic motion of anterior mitral leaflet (AML) and posterior mitral leaflet (PML). Methods: Fifty-eight adult, Dorsett-hybrid, male sheep (49 5 kg) had radiopaque markers inserted: eight around the mitral annulus, four along the central meridian (from edge to annulus) of the AML (#A(1)-#A(4)) and one on the PML edge (#P-1). True-sized Edwards Cosgrove (COS, n = 12), St Jude RSAR (St. Jude Medical, St. Paul, MN, USA) (n = 12), Carpentier-E...
Multielectrode venous catheter mapping as a high quality constraint for electrocardiographic inverse solution
Serinağaoğlu Doğrusöz, Yeşim; YILMAZ, BÜLENT; Brooks, DH (Elsevier BV, 2002-01-01)
A persistent challenge in solving inverse problems in electrocardiography is the application of suitable constraints to the calculation of cardiac sources. Whether one formulates the inverse problem in terms of epicardial potentials or activation wavefronts, the problem is physically ill-posed and hence results in numerically unstable computations. Suitable physiological constraints applied with appropriate weighting can recover useful inverse solutions. However, it is often difficult to determine the best ...
Anterior mitral leaflet curvature in the beating ovine heart: a case study using videofluoroscopic markers and subdivision surfaces
Göktepe, Serdar; Kvitting, JPE; Swanson, Julia; Ingels, Neil; Miller, Craig; Kuhl, Ellen (Springer Science and Business Media LLC, 2010-06-01)
The implantation of annuloplasty rings is a common surgical treatment targeted to re-establish mitral valve competence in patients with mitral regurgitation. It is hypothesized that annuloplasty ring implantation influences leaflet curvature, which in turn may considerably impair repair durability. This research is driven by the vision to design repair devices that optimize leaflet curvature to reduce valvular stress. In pursuit of this goal, the objective of this manuscript is to quantify leaflet curvature...
A Novel Method to Adjust Saphenous Vein Graft Lengths Using 3D Printing Models
Gocer, Hakan; Durukan, Ahmet Baris; Tunc, Osman; Naseri, Erdinc; Ercan, Ertugrul (Carden Jennings Publishing Co., 2020-01-01)
Background: The optimal length of saphenous vein grafts can be challenging in surgical coronary revascularization. It is the cornerstone for graft patency. In this study, we tried to demonstrate the value of 3D printing in determining optimal saphenous graft length.
Reduced leadset selection and performance evaluation in the inverse problem of electrocardiography for reconstructing the ventricularly paced electrograms
No, F. Gharbalchi; Serinağaoğlu Doğrusöz, Yeşim; Onak, O. N.; Weber, G-W (Elsevier BV, 2020-05-01)
Objective: Noninvasive electrocardiographic imaging (ECGI) is used for obtaining high-resolution images of the electrical activity of the heart, and is a powerful method with the potential to detect certain arrhythmias. However, there is no 'best' lead configuration in the literature to measure the torso potentials. This paper evaluates ECGI reconstructions using various reduced leadset configurations, explores whether one can find a common reduced leadset configuration that can accurately reconstruct the e...
Citation Formats
J. Kvitting et al., “Anterior Mitral Leaflet Curvature During the Cardiac Cycle in the Normal Ovine Heart,” CIRCULATION, pp. 1683–1689, 2010, Accessed: 00, 2020. [Online]. Available: