Show/Hide Menu
Hide/Show Apps
anonymousUser
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Videos
Videos
Thesis submission
Thesis submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Contact us
Contact us
Enantioselective synthesis of new chiral 2-aziridinyl phosphonates and studies of their biological activities
Date
2017-02-15
Author
Doğan, Özdemir
POLAT ÇAKIR, SIDIKA
Beksultanova, Nurzhan
ALTANLAR, NURTEN
Simsek, Duygu
KARABIYIK, HASAN
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
7
views
0
downloads
Cite This
A new series of chiral aziridinyl phosphonates has been synthesized and evaluated for antibacterial and antifungal activities. For the synthesis, a Gabriel-Cromwell reaction was used to form aziridinyl phosphonates in 52-83% yield. In order to evaluate antibacterial and antifungal activities, MIC values were measured. Although most of the compounds showed insignificant activity, two of them provided low to moderate antifungal activity.
Subject Keywords
Oxide aziridinyl phosphonate
,
Phosphine oxide
,
Terminal aziridines
,
Aldehydes
,
Derivatives
,
Lithiation
,
Arylaziridines
,
2-Phosphonates
,
Miraziridine
,
Efficient
URI
https://hdl.handle.net/11511/47313
Journal
TETRAHEDRON-ASYMMETRY
DOI
https://doi.org/10.1016/j.tetasy.2017.01.003
Collections
Department of Chemistry, Article
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
Ö. Doğan, S. POLAT ÇAKIR, N. Beksultanova, N. ALTANLAR, D. Simsek, and H. KARABIYIK, “Enantioselective synthesis of new chiral 2-aziridinyl phosphonates and studies of their biological activities,”
TETRAHEDRON-ASYMMETRY
, vol. 28, no. 2, pp. 324–329, 2017, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/47313.