Determination of selected natural hormones and endocrine disrupting compounds in domestic wastewater treatment plants by liquid chromatography electrospray ionization tandem mass spectrometry after solid phase extraction

Date

2012-01-01

Author

Muz, Melis
SÖNMEZ, MARGARET JEANNE M.
Komesli, Okan Tarik
Bakirdere, Sezgin
Gökçay, Celal Ferdi

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A new analytical method for the simultaneous determination of two natural hormones (progesterone and estrone) and two selected endocrine disrupter compounds (EDCs) (diltiazem and carbamazepine (Cbz)) was developed by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) after pre-concentration with solid phase extraction (SPE). Influent and effluent samples taken from five different wastewater treatment plants throughout Turkey namely Hurma/Antalya, Lara/Antalya, Kemer-1 and Kemer-2 and METU/Ankara were analyzed for their EDCs contents under the optimum conditions. All of the parameters in the pre-concentration step were optimized and the best recoveries for all compounds of interest were achieved at pH 7 (about 100%). Progesterone was not detected in any of the treatment plants while diltiazem was found in all samples with the exception of Lara effluent.

Subject Keywords

Personal-care products, Gas-chromatography, Acidic pharmaceuticals, Removal, Estrogens, Sewage, Substances, Surface, Samples

URI

https://hdl.handle.net/11511/51536

Journal

ANALYST

DOI

https://doi.org/10.1039/c2an15644j

Collections

Department of Environmental Engineering, Article

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Citation Formats

M. Muz, M. J. M. SÖNMEZ, O. T. Komesli, S. Bakirdere, and C. F. Gökçay, “Determination of selected natural hormones and endocrine disrupting compounds in domestic wastewater treatment plants by liquid chromatography electrospray ionization tandem mass spectrometry after solid phase extraction,” ANALYST, pp. 884–889, 2012, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/51536.