Effects of Ethylene Oxide Resterilization and In-vitro Degradation on Mechanical Properties of Partially Absorbable Composite Hernia Meshes

Endoğan Tanır, Tuğba
Kulacoglu, H.
Serbetci, K.
Kiyak, G.
Hasırcı, Nesrin
Background and Aim: Prosthetic mesh repair for abdominal wall hernias is widely used because of its technical simplicity and low hernia recurrence rates. The most commonly used material is pure polypropylene mesh, although newer composite materials are recommended by some centers due to their advantages. However, these meshes are more expensive than pure polypropylene meshes. Resterilization of a pure polypropylene mesh has been shown to be quite safe, and many centers prefer slicing a large mesh into smaller pieces, suitable for any hernia type or defect size. Nevertheless there is no data about the safety after resterilization of the composite meshes. The present study was carried out to investigate the effects of resterilization and in vitro degradation in phosphate buffered saline solution on the physical structure and the mechanical properties of partially absorbable lightweight meshes.


Basic fibroblast growth factor loaded polypropylene meshes in repair of abdominal wall defects in rats
Heybeli, T.; Kulacoglu, H.; GENÇ, VOLKAN; Ergul, Z.; Ensari, C.; Kızıltay, Aysel; Yilmazer, D.; Serbetci, K.; Hasırcı, Nesrin (2010-11-01)
Background and Aim: Incisional hernia following laparotomy and recurrent herniation after its repair are still common problems in spite of mesh augmentation. The underlying biological mechanism may be related to collagen metabolism. Recently, some members of growth factors family have been tested in the prevention of wound failure and incisonal hernia formation. Growth factors may promote fibroblast proliferation and collagen deposition. In the present study, we searched the effects of basic fibroblast grow...
Effects of resterilization on mechanical properties of polypropylene meshes
Serbetci, Kemal; Kulacoglu, Hakan; Devay, Ali Onder; Hasırcı, Nesrin (2007-09-01)
Background: The re-use of sterile packaged polypropylene meshes in hernia surgery is not recommended by the manufacturers. However, especially in developing and underdeveloped countries, many surgeons are obliged to re-use the mesh pieces after resterilization because of economic problems. The purpose of this study was to determine the effects of ethylene oxide and autoclave resterilization on the mechanical properties of polypropylene meshes.
Effect of MgF2 on hot pressed hydroxylapatite and monoclinic zirconia composites
Evis, Zafer (Springer Science and Business Media LLC, 2007-06-01)
Hydroxylapatite (HA) has been widely used in biomedical applications because of its excellent biocompatibility in the human body. A total of 25 wt% monoclinic (m) zirconia-HA composites (with and without 5 wt% MgF2) were synthesized to investigate their mechanical properties and phase stability. In HA-m-ZrO2 composites, HA and m-ZrO2 reacted to form CaZrO3 when there was no F- present in the composite and M-ZrO2 partially transformed to tetragonal ZrO2. When MgF2 was added into the system, it improved the t...
Effects of the doping concentration of boron on physicochemical, mechanical, and biological properties of hydroxyapatite
Jodati, Hossein; Tezcaner, Ayşen; Alshemary, Ammar Z.; Şahin, Volkan; Evis, Zafer (2022-01-01)
© 2022 Elsevier Ltd and Techna Group S.r.l.Ion doping is an approach to modify properties of materials, like hydroxyapatite (HA), that contributes to designing biomaterials with desired characteristics applicable in bone defect treatments. Recently, boron (B) has been noticed in biomaterial fields due to its beneficial effects on formation, growth, and quality of bone. In this study, B-doped HA nanoparticles with different molar concentrations of B (0.05, 0.1, 0.25, and 0.5) were synthesized through microwa...
Development of microcarrier systems for bone tissue engineering
Aydoğdu, Hazal; Tezcaner, Ayşen; Baran, Erkan Türker; Department of Biomedical Engineering (2015)
Current strategies in bone tissue engineering have largely focused on development of carrier systems for repair and regeneration of bone tissue defects. The microcarrier systems offer an efficient method of delivery of cells with non-invasive injectable system. In this study, three-dimensional hydrogel microspheres were developed via water-in-oil emulsion method. In the first part of the thesis, porous pullulan (PULL) microspheres, with average size of 153±46 µm, were prepared and the surface of the microsp...
Citation Formats
T. Endoğan Tanır, H. Kulacoglu, K. Serbetci, G. Kiyak, and N. Hasırcı, “Effects of Ethylene Oxide Resterilization and In-vitro Degradation on Mechanical Properties of Partially Absorbable Composite Hernia Meshes,” CHIRURGIA, pp. 840–848, 2013, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/54435.