A photodynamic pathway to apoptosis induced by hypericin in human myeloma ARH-77 cell line: Possible relevance to photodynamic therapy.

Avcu, F
Ural, AU
Baran, Y
Sobaci, G
Deveci, M
Cetin, T
Pekel, A
Sarper, M
Elci, P
Gündüz, Ufuk
47th Annual Meeting of the American-Society-of-Hematology


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Tumer, Tugba Boyunegmez; Ulusoy, Gulen; Adalı, Orhan; Sahin, Gurses; Gozdasoglu, Sevgi; Arinc, Ennel (Wiley, 2007-10-01)
6-Mercaptopurine (6MP) is an essential anticancer drug used in the treatment of childhood acute lymphoblastic leukemia (ALL). Thiopurine methyltransferase (TPMT) polymorphisms are the major determinants of interindividual differences in the severe toxicity or efficacy of 6MP Four variant alleles, TPMT*2, TPMT*3A, TPMT*3B, and TPMT*3C, are responsible over the 80% of low or undetectable enzyme activity. The frequencies of these variants were investigated among 106 children with ALL in Turkish population. TPM...
Expression of multidrug resistance 1, lung resistance protein and breast cancer resistance protein genes in chronic lymphocytic and chronic myelogeneous leukemia.
Ural, A. Ugur; Iseri, Ozlem Darcansoy; Mutlu, Pelin; Kars, Meltem Demirel; Avcu, Ferit; Gündüz, Ufuk; Ilhan, Osman (2006-11-16)
Role hydrology, sewage effluent diversion and fish on mass balance of nutrients in a system of shallow lakes Mogan and Eymir, Turkey
Karapınar, Burcu; Beklioğlu, Meryem; Department of Biology (2005)
In this study, annual total phosphorus (TP) budget and dissolved inorganic nitrogen (DIN) load were constructed for Lakes Mogan and Eymir for the period of eight years from 1997 to 2004 and the period of ten years covering from 1993 to 1995 and 1997 to 2004, respectively. Lake Mogan experienced seasonal and interannual water level fluctuations. Low water level experienced in 2001 led to decrease in the in-lake TP amount whereas 2-fold increase in the in-lake DIN amount was recorded. Also, high hydraulic res...
Anti-Cancer Effects of Clofazimine As a Single Agent and in Combination with Cisplatin in Multiple Myeloma
Durusu, Ipek; Hüsnügil, Hepşen Hazal; Atas, Heval; Biber, Aysenur; Gerekci, Selin; Gulec, Aliye Ezgi; Özen, Can (2016-12-02)
Multiple Myeloma (MM) is a malignant neoplasm of bone marrow plasma B cells with high morbidity. Clofazimine (CLF) is an FDA-approved leprostatic, anti-tuberculosis, and anti-inflammatory drug that was previously shown to have growth suppression effect on various cancer types such as hepatocellular, lung, cervix, esophageal, colon, and breast cancer as well as melanoma, neuroblastoma, and leukemia. The objective of this study was to evaluate the anticancer effect and mechanism of CLF on U266 MM cell line. C...
A study of the relative dominance of selected anaerobic sulfate-reducing bacteria in a continuous bioreactor by fluorescence in situ hybridization
İçgen, Bülent; Harrıson, S.T.L. (Springer Science and Business Media LLC, 2007-01-01)
The diversity and the community structure of sulfate-reducing bacteria (SRB) in an anaerobic continuous bioreactor used for treatment of a sulfate-containing wastewater were investigated by fluorescence in situ hybridization. Hybridization to the 16S rRNA probe EUB338 for the domain Bacteria was performed, followed by a nonsense probe NON338 as a control for nonspecific staining. Sulfate-reducing consortia were identified by using five nominally genus-specific probes (SRB129 for Desulfobacter, SRB221 for De...
Citation Formats
F. Avcu et al., “A photodynamic pathway to apoptosis induced by hypericin in human myeloma ARH-77 cell line: Possible relevance to photodynamic therapy.,” Atlanta, GA, 2005, vol. 106, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/55803.