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Effects of selenium supplementation on rat heart apex and right ventricle myocardia by using FTIR spectroscopy: A cluster analysis and neural network approach
Date
2008-10-01
Author
TOYRAN AL OTAİBİ, NESLİHAN
Severcan, Feride
Severcan, Mete
TURAN, Belma
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The effects of selenium supplementation on apex and right ventricle myocardia of the rat heart were investigated using Fourier transform infrared (FTIR) spectroscopy by examining the changes in the frequency values of major absorptions arising from lipids and proteins. Cluster analysis was used to discriminate the selenium treated group from the control by utilizing two distinct spectral regions, belonging to absorptions arising from lipids and proteins, respectively. In addition, protein secondary structures were predicted using neural network analysis. The results suggest that selenium treatment at a non-toxic dose causes some significant structural alterations in lipids and proteins of rat heart apex and right ventricle myocardia, which might be revealing a slight deleterious effect of selenium supplementation.
Subject Keywords
Food Science
,
Analytical Chemistry
,
General Medicine
URI
https://hdl.handle.net/11511/56702
Journal
FOOD CHEMISTRY
DOI
https://doi.org/10.1016/j.foodchem.2008.02.044
Collections
Department of Biology, Article
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N. TOYRAN AL OTAİBİ, F. Severcan, M. Severcan, and B. TURAN, “Effects of selenium supplementation on rat heart apex and right ventricle myocardia by using FTIR spectroscopy: A cluster analysis and neural network approach,”
FOOD CHEMISTRY
, pp. 590–597, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/56702.