Effects of selenium supplementation on rat heart apex and right ventricle myocardia by using FTIR spectroscopy: A cluster analysis and neural network approach

Date

2008-10-01

Author

TOYRAN AL OTAİBİ, NESLİHAN
Severcan, Feride
Severcan, Mete
TURAN, Belma

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The effects of selenium supplementation on apex and right ventricle myocardia of the rat heart were investigated using Fourier transform infrared (FTIR) spectroscopy by examining the changes in the frequency values of major absorptions arising from lipids and proteins. Cluster analysis was used to discriminate the selenium treated group from the control by utilizing two distinct spectral regions, belonging to absorptions arising from lipids and proteins, respectively. In addition, protein secondary structures were predicted using neural network analysis. The results suggest that selenium treatment at a non-toxic dose causes some significant structural alterations in lipids and proteins of rat heart apex and right ventricle myocardia, which might be revealing a slight deleterious effect of selenium supplementation.

Subject Keywords

Food Science, Analytical Chemistry, General Medicine

URI

https://hdl.handle.net/11511/56702

Journal

FOOD CHEMISTRY

DOI

https://doi.org/10.1016/j.foodchem.2008.02.044

Collections

Department of Biology, Article

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Citation Formats

N. TOYRAN AL OTAİBİ, F. Severcan, M. Severcan, and B. TURAN, “Effects of selenium supplementation on rat heart apex and right ventricle myocardia by using FTIR spectroscopy: A cluster analysis and neural network approach,” FOOD CHEMISTRY, pp. 590–597, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/56702.