Metal triflates-catalyzed conjugate addition of homochiral Pyrroles to alpha,beta-unsaturated esters

2004-10-18
Unaleroglu, C
Temelli, B
Demir, Ayhan Sıtkı
The Friedel-Crafts reaction of homochiral pyrrole derivatives with alpha,beta-unsaturated esters catalyzed by metal triflates furnished conjugate addition products. The best yields were obtained by using yttrium triflate and methyl 4-phenyl-2-oxobut-3-enoate (2a). The addition worked regioselectively at C-5 of pyrrole. The diastereoisomers were separated by column chromatography.
SYNTHESIS-STUTTGART

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Citation Formats
C. Unaleroglu, B. Temelli, and A. S. Demir, “Metal triflates-catalyzed conjugate addition of homochiral Pyrroles to alpha,beta-unsaturated esters,” SYNTHESIS-STUTTGART, pp. 2574–2578, 2004, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57347.