Metal triflates-catalyzed conjugate addition of homochiral Pyrroles to alpha,beta-unsaturated esters

Date

2004-10-18

Author

Unaleroglu, C
Temelli, B
Demir, Ayhan Sıtkı

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The Friedel-Crafts reaction of homochiral pyrrole derivatives with alpha,beta-unsaturated esters catalyzed by metal triflates furnished conjugate addition products. The best yields were obtained by using yttrium triflate and methyl 4-phenyl-2-oxobut-3-enoate (2a). The addition worked regioselectively at C-5 of pyrrole. The diastereoisomers were separated by column chromatography.

Subject Keywords

Organic Chemistry, Catalysis

URI

https://hdl.handle.net/11511/57347

Journal

SYNTHESIS-STUTTGART

DOI

https://doi.org/10.1055/s-2004-831195

Collections

Department of Chemistry, Article

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Citation Formats

C. Unaleroglu, B. Temelli, and A. S. Demir, “Metal triflates-catalyzed conjugate addition of homochiral Pyrroles to alpha,beta-unsaturated esters,” SYNTHESIS-STUTTGART, pp. 2574–2578, 2004, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57347.