Fermentation and oxygen transfer characteristics in recombinant human growth hormone production by Pichia pastoris in sorbitol batch and methanol fed-batch operation

Date

2010-02-01

Author

Çalık, Pınar
Soyaslan, Elif S.
Sahin, Merve
Taspinar, Hatice
Acik, Eda
Bayraktar, Eda

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BACKGROUND: The influence of methanol feed rate on recombinant human growth hormone (rhGH) production by Pichia pastoris hGH-Mut(+) in medium containing sorbitol was investigated at three different specific growth rates (mu), namely, 0.02 (MS-0.02), 0.03 (MS-0.03), and 0.04 (MS-0.04).

Subject Keywords

Biotechnology, Fuel Technology, Inorganic Chemistry, Renewable Energy, Sustainability and the Environment, Organic Chemistry, Waste Management and Disposal, Pollution, General Chemical Engineering

URI

https://hdl.handle.net/11511/57540

Journal

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

DOI

https://doi.org/10.1002/jctb.2292

Collections

Department of Chemical Engineering, Article

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Citation Formats

P. Çalık, E. S. Soyaslan, M. Sahin, H. Taspinar, E. Acik, and E. Bayraktar, “Fermentation and oxygen transfer characteristics in recombinant human growth hormone production by Pichia pastoris in sorbitol batch and methanol fed-batch operation,” JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, pp. 226–233, 2010, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57540.