Mesenchymal Stem Cells and Nano-Bioceramics for Bone Regeneration

Date

2016-01-01

Author

Kankilic, Berna
Kose, Sevil
KORKUSUZ, PETEK
Timucin, Muharrem
Korkusuz, Feza

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Orthopedic disorders and trauma usually result in bone loss. Bone grafts are widely used to replace this tissue. Bone grafts excluding autografts unfortunately have disadvantages like evoking immune response, contamination and rejection. Autografts are of limited sources and optimum biomaterials that can replace bone have been searched for several decades. Bioceramics, which have the similar inorganic structure of natural bone, are widely used to regenerate bone or coat metallic implants. As people continuously look for a higher life quality, there are developments in technology almost everyday to meet their expectations. Nanotechnology is one of such technologies and it attracts everyone's attention in biomaterial science. Nano scale biomaterials have many advantages like larger surface area and higher biocompatibility and these properties make them more preferable than micro scale. Also, stem cells are used for bone regeneration besides nano-bioceramics due to their differentiation characteristics. This review covers current research on nano-bioceramics and mesenchymal stem cells and their role in bone regeneration.

Subject Keywords

Bioceramics, Bone, Mesenchymal stem cells, Nano scale, Regeneration, Tissue engineering

URI

https://hdl.handle.net/11511/62974

Journal

CURRENT STEM CELL RESEARCH & THERAPY

DOI

https://doi.org/10.2174/1574888x10666150202150518

Collections

Department of Physical Education and Sports, Article

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Citation Formats

B. Kankilic, S. Kose, P. KORKUSUZ, M. Timucin, and F. Korkusuz, “Mesenchymal Stem Cells and Nano-Bioceramics for Bone Regeneration,” CURRENT STEM CELL RESEARCH & THERAPY, pp. 487–493, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/62974.