Synthesis of (3,6-dihydro-2H-pyran-2-yl)phosphonate derivatives and investigation of catalyst effect on frontier molecular orbitals using DFT method

Date

2016-01-01

Author

Hossain, Md Shakhawoat
POLAT ÇAKIR, SIDIKA
Ozpinar, Gul Altinbas
Nadeem, Said
Demir, Ayhan Sıtkı

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Hetero Diels-Alder (HDA) reactions between 2,3-dimethyl-1,3-butadiene and diethyl ester of aroyl phosphonates catalyzed by AlCl3 to afford (3,6-dihydro-2H-pyran-2-yl) phosphonate derivatives were investigated. Aroyl phosphonates with electron-withdrawing groups generally resulted in better isolated chemical yields. A stoichiometric amount of AlCl3 rather than a catalytic amount was necessary to activate the cycloaddition reaction. The amount of AlCl3 catalyst and its effect on LUMO of ethyl ester benzoyl phosphonate were also investigated by performing density functional theory (DFT) (B97D/6-31+G(d,p)) computations in dichloromethane. An increased loading of AlCl3 induced a considerable decrease in the LUMO energy of ethyl ester of benzoyl phosphonate. The computed Gibbs free activation energy is 17.03kcal/mol in DCM at 0 degrees C using the same computational level.

Subject Keywords

Inorganic Chemistry, Organic Chemistry, Biochemistry

URI

https://hdl.handle.net/11511/62978

Journal

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS

DOI

https://doi.org/10.1080/10426507.2016.1166502

Collections

Department of Chemistry, Article

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Citation Formats

M. S. Hossain, S. POLAT ÇAKIR, G. A. Ozpinar, S. Nadeem, and A. S. Demir, “Synthesis of (3,6-dihydro-2H-pyran-2-yl)phosphonate derivatives and investigation of catalyst effect on frontier molecular orbitals using DFT method,” PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, pp. 1262–1267, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/62978.