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Synthesis of (3,6-dihydro-2H-pyran-2-yl)phosphonate derivatives and investigation of catalyst effect on frontier molecular orbitals using DFT method
Date
2016-01-01
Author
Hossain, Md Shakhawoat
POLAT ÇAKIR, SIDIKA
Ozpinar, Gul Altinbas
Nadeem, Said
Demir, Ayhan Sıtkı
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Hetero Diels-Alder (HDA) reactions between 2,3-dimethyl-1,3-butadiene and diethyl ester of aroyl phosphonates catalyzed by AlCl3 to afford (3,6-dihydro-2H-pyran-2-yl) phosphonate derivatives were investigated. Aroyl phosphonates with electron-withdrawing groups generally resulted in better isolated chemical yields. A stoichiometric amount of AlCl3 rather than a catalytic amount was necessary to activate the cycloaddition reaction. The amount of AlCl3 catalyst and its effect on LUMO of ethyl ester benzoyl phosphonate were also investigated by performing density functional theory (DFT) (B97D/6-31+G(d,p)) computations in dichloromethane. An increased loading of AlCl3 induced a considerable decrease in the LUMO energy of ethyl ester of benzoyl phosphonate. The computed Gibbs free activation energy is 17.03kcal/mol in DCM at 0 degrees C using the same computational level.
Subject Keywords
Inorganic Chemistry
,
Organic Chemistry
,
Biochemistry
URI
https://hdl.handle.net/11511/62978
Journal
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
DOI
https://doi.org/10.1080/10426507.2016.1166502
Collections
Department of Chemistry, Article
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M. S. Hossain, S. POLAT ÇAKIR, G. A. Ozpinar, S. Nadeem, and A. S. Demir, “Synthesis of (3,6-dihydro-2H-pyran-2-yl)phosphonate derivatives and investigation of catalyst effect on frontier molecular orbitals using DFT method,”
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
, pp. 1262–1267, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/62978.