Optimization studies on the features of an activated charcoal-supported urease system

Date

1996-08-01

Author

Kibarer, GD
Akovali, G

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The adsorption of urease onto a well-defined solid support, petroleum-based activated charcoal, has been achieved to provide the enzymatic hydrolysis of urea. In order to produce a biocompatible surface, the enzyme support system has been coated with hexamethyldisiloxane through plasma polymerization. The quality of the resulting coat was tested by electronic spectroscopy for chemical analysis and scanning electron microscopy techniques. Studies on the adsorption of urease, and activity and stability of the enzyme on the support have been in the direction to optimize the features of the charcoal-supported urease and improve its availability for further use in clinical applications. (C) 1996 Elsevier Science Limited.

Subject Keywords

Biophysics, Mechanics of Materials, Bioengineering, Biomaterials, Ceramics and Composites

URI

https://hdl.handle.net/11511/64743

Journal

BIOMATERIALS

DOI

https://doi.org/10.1016/0142-9612(96)89771-7

Collections

Department of Chemistry, Article

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Citation Formats

G. Kibarer and G. Akovali, “Optimization studies on the features of an activated charcoal-supported urease system,” BIOMATERIALS, pp. 1473–1479, 1996, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/64743.