Firing coincidences between neighboring retinal ganglion cells: inside information or epiphenomenon?

Date

2002-10-01

Author

Levine, MW
Castaldo, K
Kasapoglu, MB

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Retinal ganglion cells often fire impulses in synchrony; is this synchronization an irrelevant by-product of processing shared inputs, or does it encode information? We examined the rate of occurrence of coincident impulses from pairs of ganglion cells responding to stimuli that varied along several dimensions. We find that coincidences convey little if any additional information about simple static stimuli beyond what could be determined from the firing rates of the two cells considered separately. In fact, at least one of the separate cells generally provided a better information channel than the coincidence rate, implying that under these conditions ganglion cells do not employ a strategy of encoding by coincidences. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

Subject Keywords

General Biochemistry, Genetics and Molecular Biology, Modelling and Simulation, Statistics and Probability, Applied Mathematics, General Medicine

URI

https://hdl.handle.net/11511/66537

Journal

BIOSYSTEMS

DOI

https://doi.org/10.1016/s0303-2647(02)00072-2

Collections

Department of Biology, Article

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Citation Formats

M. Levine, K. Castaldo, and M. Kasapoglu, “Firing coincidences between neighboring retinal ganglion cells: inside information or epiphenomenon?,” BIOSYSTEMS, pp. 139–146, 2002, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/66537.