Meso-piperidine linked bodipys: Synthesis, fluorescent properties and biological evaluation

Date

2019-01-01

Author

Ecik, Esra Tanriverdi
Kazan, Hasan Huseyin
Sengul, Ibrahim F.
KANDEMİR, HAKAN
Cosut, Bunyemin

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The synthesis and characterization of meso-piperidine linked Bodipy starting from 4-(2-(piperidine-1-yl)ethoxy) benzaldehyde was described. Meso-piperidine linked Bodipy was subsequently used for the construction of distyryl-piperidine-Bodipy and distyryl-morpholine-Bodipy via Knoevenagel type reaction. The photophysical properties including molar extinction coefficient, fluorescence lifetime and fluorescence quantum yield of Bodipys were investigated in ethanol solution. The targeted compounds were also assessed in live cell imaging and cytotoxicity studies by using breast cancer cell line, MCF-7 in vitro.

Subject Keywords

Biophysics, Atomic and Molecular Physics, and Optics, Biochemistry, General Chemistry, Condensed Matter Physics

URI

https://hdl.handle.net/11511/68105

Collections

Department of Biology, Article