Effects of human granulocyte-colony stimulating factor on fracture healing in rats

Date

2005-08-01

Author

Bozlar, M
Aslan, B
Kalaci, A
Baktiroglu, L
Yanat, AN
Tasci, A

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Objective: Granulocyte colony stimulation factor (G-CSF) is generally used to prevent and cure the neutropenia associated with chemotherapy and bone marrow transplantation. In addition to its effects on neutrophil function, G-CSF was found to have the characteristic of modulating the cytokines in the inflammatory response. Then, the question to answer is whether it has any effect on fracture healing and to what extent? In this study, we test the effects of G-CSF on the healing of tibia fracture in a rat model.

Subject Keywords

Growth-factors, Neutropenia, Chemotherapy, Macrophage

URI

https://hdl.handle.net/11511/68246

Journal

SAUDI MEDICAL JOURNAL

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Unclassified, Article

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Citation Formats

M. Bozlar, B. Aslan, A. Kalaci, L. Baktiroglu, A. Yanat, and A. Tasci, “Effects of human granulocyte-colony stimulating factor on fracture healing in rats,” SAUDI MEDICAL JOURNAL, pp. 1250–1254, 2005, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/68246.