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Insulin with a stable basal release profile
Date
2011-5-12
Author
Pohl, Roderike
Kashyap, Nandini
Hauser, Robert
Özhan, Koray
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A basal insulin formulation composed of insulin, preferably insulin glargine, injectable zinc and injectable iron compounds as precipitating and/or stabilizing agents has been developed for subcutaneous, intradermal or intramuscular administration. The formulation is designed to form a precipitate of insulin following injection, creating a slow releasing "basal insulin" over a period of 12 to 24 hours.
URI
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2011143421&_cid=P12-KJTN7W-94705-1
https://hdl.handle.net/11511/70176
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Graduate School of Marine Sciences, Patent / Utility Model
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Insulin with a basal release profile
Pohl, Roderike; Kashyap, Nandini; Hauser, Robert; Özhan, Koray; Steıner, Solomon S. (Dünya Fikri Mülkiyet Teşkilatı, 2009-9-2)
A clear basal insulin formulation composed of insulin (preferably human recombinant insulin), buffering agents, precipitating agents, and/or stabilizing agents for subcutaneous, intradermal or intramuscular administration. The formulation is designed to form a precipitate of insulin following injection, creating a slow releasing "basal insulin" over a period of 12 to 24 hours, which can be varied by compositional changes to tailor the release profile to the needs of the individual diabetic patient.
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R. Pohl, N. Kashyap, R. Hauser, and K. Özhan, “Insulin with a stable basal release profile,” 00, 2011.