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Electrospinning Silk with Selenium for Antibacterial Skin Applications
Date
2014-12-31
Author
Chung, Stanley
Tran, Phong
Ercan, Batur
Webster, Thomas
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https://hdl.handle.net/11511/72551
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Electrospun Silk Doped with Selenium for Antibacterial Skin Applications
Chung, Stanley; Ercan, Batur; Webster, Thomas J.; Phong Tran, Phong Tran (2014-01-01)
Skin is the largest organ by surface area and provides the primary defense against microbes, viruses, and other harmful environmental interactions. Silk is widely used as a cosmetic additive and has been investigated for skin regeneration because of its beneficial properties for skin application : promotion of collagen synthesis, re-epithelialization, wound healing, atopic dermatitis alleviation, and scar reduction. However, pure silk shows negligible or even negative antibacterial properties. Here, we prop...
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Electrospinning, which is a fiber fabrication technique using electrical forces to produce fibers with diameters ranging from nanometers to several micrometers, can be used to prepare materials mimicking the extracellular matrix proteins for potential use as tissue engineering scaffolds. In this study, nanofibrous mats of chitosan (CH) and poly(lactic acid-co-glycolic acid) (PLGA) having fiber diameters between 167 to 525 nm, and containing hydroxyapatite (HAp), were prepared by electrospinning technique. M...
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Nanofibers, which have high surface area to volume ratio and better mechanical properties, are nanomaterials that both industry and scientists have started to show great attention in the last two decades. They are used in many areas such as life and filtration sciences, sensors, and composite reinforcement etc. Among five main production types, electrospinning is the best candidate for further development with a wide range of opportunities to be applied to all types of polymers and ceramics. This method use...
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Cyclodextrin functionalized PMMA nanofibers (PMMA/CD) were successfully produced by electrospinning technique with the goal to develop functional nanowebs. Bead-free uniform electrospun PMMA/CD nanofibers were obtained from a homogeneous solution of CDs and PMMA in dimethylformamide (DMF) using three different types of CDs, alpha-CD, beta-CD and gamma-CD. The electrospinning conditions were optimized in order to form bead-free PMMA/CD nanofibers by varying the concentrations of PMMA and CDs in the solutions...
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S. Chung, P. Tran, B. Ercan, and T. Webster, “Electrospinning Silk with Selenium for Antibacterial Skin Applications,” 2014, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/72551.