A Crack Phase-field Model to Analyze Aortic Dissections

Date

2019-09-05

Author

Holzapfel, Gerhard A.
Gültekin, Osman
Hager, Sandra P.
Dal, Hüsnü

Metadata

Show full item record

Item Usage Stats

214
views

0
downloads

This study analyzes the lethal clinical condition of aortic dissections from a numerical point of view.On the basis of our previous contributions [1,2], we apply a holistic geometrical approach to fracture,namely the crack phase-field, which inherits the intrinsic features of gradient damage and variationalfracture mechanics. The continuum framework captures anisotropy, is thermodynamically consistentand based on finite strains. The balance of linear momentum and the crack evolution equation governthe coupled mechanical and phase-field problem. The solution scheme features the robust one–passoperator–splitting algorithm upon temporal and spatial discretizations. Based on experimental data ofdiseased human thoracic aortic samples, the elastic material parameters are identified followed by asensitivity analysis of the anisotropic phase-field model. Finally, we simulate an incipient propagation ofan aortic dissection within a multi–layered segment of a thoracic aorta that involves a prescribed initialtear [3]. The finite element results demonstrate a severe damage zone around the initial tear, exhibit arather helical crack pattern, which aligns with the fiber orientation.

URI

https://www.researchgate.net/publication/337739177_A_Crack_Phase-field_Model_to_Analyze_Aortic_Dissections
https://hdl.handle.net/11511/76483
https://congress.cimne.com/complas2019/admin/files/fileabstract/a447.pdf

Conference Name

15th International Conference on Computational Plasticity–Fundamentals and Applications, 2019

Collections

Department of Mechanical Engineering, Conference / Seminar

Suggestions

OpenMETU
Core

A multiscale model for eccentric and concentric cardiac growth through sarcomerogenesis Göktepe, Serdar; Parker, Kit; Kuhl, Ellen (2010-08-07) We present a novel computational model for maladaptive cardiac growth in which kinematic changes of the cardiac chambers are attributed to alterations in cytoskeletal architecture and in cellular morphology. We adopt the concept of finite volume growth characterized through the multiplicative decomposition of the deformation gradient into an elastic part and a growth part. The functional form of its growth tensor is correlated to sarcomerogenesis, the creation and deposition of new sarcomere units. In respo...
A biomimetic growth factor delivery strategy for enhanced regeneration of iliac crest defects Huri, Pinar Yilgor; Huri, Gazi; Yasar, Umit; UÇAR , YURDANUR; DİKMEN, NURTEN; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat (2013-06-01) The importance of provision of growth factors in the engineering of tissues has long been shown to control the behavior of the cells within the construct and several approaches were applied toward this end. In nature, more than one type of growth factor is known to be effective during the healing of tissue defects and their peak concentrations are not always simultaneous. One of the most recent strategies includes the delivery of a combination of growth factors with the dose and timing to mimic the natural ...
A multi-layered graphical model of the relation among SNPS, GENES, and pathways based on subgraph search Ersoy, Gökhan; Aydın Son, Yeşim; Can, Tolga; Department of Bioinformatics (2015) The analysis of Single Nucleotide Polymorphisms (SNPs) through Genome Wide Association Studies (GWAS) presents great potential for describing disease loci and gaining insight into the underlying etiology of diseases. Recently described combined p-value approach allows identification of associations at gene and pathway level. The integrated programs like METU-SNP produce simple lists of either SNP id/gene id/pathway title and their p-values and significance status or SNP id/disease id/pathway information. In...
Development of a regression model for the life assessment of open-hole specimens with double through cracks utilizing stress intensity factor calculations via XFEM Shabestari, S. Sohrab Heidari; Kayran, Altan (Elsevier BV; 2019-01-01) Development of a regression model for the life assessment of open-hole specimens with double through cracks utilizing stress intensity factor calculations via XFEM
A Phase-field Approach to Model Aortic Dissections Gültekin, Osman; Dal, Hüsnü; Holzapfel, Gerhard A. (null; 2018-07-06) Physiological and pathological aspects of aortic dissection are important issues in medical science , and undoubtedly require a deeper understanding of the respective mechanics that is behind these phenomenon. This has rendered computational mechanics very important to improve and even guide monitoring and preoperative planning [1]. In particular, the in silico estimation of the macro-scopic crack initiation and its propagation associated with aortic dissection purports valuable data for the clinics. The pr...

Citation Formats

G. A. Holzapfel, O. Gültekin, S. P. Hager, and H. Dal, “A Crack Phase-field Model to Analyze Aortic Dissections,” presented at the 15th International Conference on Computational Plasticity–Fundamentals and Applications, 2019, Barcelona, İspanya, 2019, Accessed: 00, 2021. [Online]. Available: https://www.researchgate.net/publication/337739177_A_Crack_Phase-field_Model_to_Analyze_Aortic_Dissections.