Regulation of MRPl Gene Expression by Etoposide-Loaded PHB Coated Magnetic Nanoparticles in Etoposide Resistance MCF-7 Cells.

2017-05-12
Yalçın Azarkan, Serap
Gündüz, Ufuk

Suggestions

Regulation of CpG-induced immune activation by suppressive oligodeoxynucleotides.
Klinman, DM; Zeuner, R; Yamada, H; Gürsel, Mayda; Currie, D; Gursel, I (Wiley, 2003-12-01)
Bacterial DNA and synthetic oligodeoxynucleotides (ODN) containing unmethylated "CpG motifs" stimulate an innate immune response characterized by the production of cytokines, chemokines, and polyreactive Igs that promote host survival following infectious challenge. Yet CpG-driven immune activation can have deleterious consequences, such as increasing the host's susceptibility to autoimmune disease. The immunomodulatory activity of CpG DNA can be blocked by DNA containing "suppressive" motifs. This work exp...
REGULATION OF BIOSYNTHESIS OF BACILYSIN BY BACILLUS-SUBTILIS
Özcengiz, Gülay; DEMAIN, AL (Springer Science and Business Media LLC, 1990-10-01)
REGULATION OF M2-TYPE PYRUVATE-KINASE FROM HUMAN MENINGIOMA BY ALLOSTERIC EFFECTORS FRUCTOSE 1,6 DIPHOSPHATE AND L-ALANINE
MELLATI, AA; YUCEL, M; ALTINORS, N; Gündüz, Ufuk (1992-01-01)
In the present study the mechanism of action of M2-type pyruvate kinase from human meningioma in the simultaneous presence of fructose 1,6 diphosphate and L-alanine was investigated. Purified pyruvate kinase from human meningioma was allosterically inhibited by L-alanine with respect to substrates phosphoenolpyruvate and ADP. The inhibitory effects of L-alanine was partially removed by fructose 1,6 diphosphate. The purified enzyme was slightly susceptible to ATP inhibition.
Regulation of Cytoskeletal Dynamics during T Cell Activation by Substrate Stiffness
Özçelikkale, Altuğ; Upadhyaya, Arpita (2018-03-07)
T lymphocytes are an integral part of the adaptive immune response. The detection of infectious agents critically depends on the interaction of T cells with antigen presenting cells, which have varying mechanical stiffness and complex topological features. It has been recently recognized that T cell activation is regulated both by stiffness of the antigen presenting surface and by cytoskeletal forces which partially arise from actomyosin contractility. However, the relationship between stiffness and ...
Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators
Muyan, Mesut; Yasar, Pelin; Ayaz, Gamze; User, Sirma Damla; Kazan, Hasan Huseyin; Huang, Yanfang (2015-08-21)
Estrogen receptor a (ER alpha), as a ligand-dependent transcription factor, mediates 17 beta-estradiol (E2) effects. ERa is a modular protein containing a DNA binding domain (DBD) and transcription activation domains (AD) located at the amino-and carboxyl-termini. The interaction of the E2-activated ERa dimer with estrogen response elements (EREs) of genes constitutes the initial step in the ERE-dependent signaling pathway necessary for alterations of cellular features. We previously constructed monomeric t...
Citation Formats
S. Yalçın Azarkan and U. Gündüz, “Regulation of MRPl Gene Expression by Etoposide-Loaded PHB Coated Magnetic Nanoparticles in Etoposide Resistance MCF-7 Cells.,” 2017, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/76644.