Anodized Tantalum Surfaces for Orthopedic Applications

Uslu, Ece
Ercan, Batur
Currently used implant materials do not suffice the needs of patients mainly due to their poor osseointegration with the juxtaposed bone tissue, which ultimately leads to failure of the implant. To overcome this issue, better orthopedic implants exhibiting bioactive characteristics are required. Tantalum is a good candidate as a new generation orthopedic implant materials due to its superior mechanical and chemical properties compared to the currently-used metallic implant materials. However, its bioinert nature prevents formation of firm and lasting interface with the juxtaposed bone. Herein, tantalum was anodized using different concentrations of aqueous and concentrated H2SO4-HF electrolytes under 10-30V electrical potential up to 2 hours to fabricate bioactive nanotubular, nanocoral and nanodimple surface morphologies on tantalum. To examine the bioactivity of the surface, simulated body fluid analysis was conducted up to 21 days. Findings showed that nanofeatured tantalum surfaces promote formation of CaP minerals.
19th International Metallurgy & Materials Congress


Anodized Nanostructured 316L Stainless Steel Enhances Osteoblast Functions and Exhibits Anti-Fouling Properties
Erdoğan, Yaşar Kemal; Ercan, Batur (2023-01-01)
Poor osseointegration and infection are among the major challenges of 316L stainless steel (SS) implants in orthopedic applications. Surface modifications to obtain a nanostructured topography seem to be a promising method to enhance cellular interactions of 316L SS implants. In this study, arrays of nanodimples (NDs) having controlled feature sizes between 25 and 250 nm were obtained on 316L SS surfaces by anodic oxidation (anodization). Results demonstrated that the fabrication of NDs increased the surfac...
Passive Haptic Interface with MR-Brakes for Dental Implant Surgery
Senkal, Doruk; Gurocak, Hakan; Konukseven, Erhan İlhan (MIT Press - Journals, 2011-06-01)
In this research a passive haptic interface is explored as a surgical aid for dental implant surgery. The placement of a dental implant is critical since positioning mistakes can lead to permanent damage in the nerves controlling the lips, long lasting numbness, and failure of the implant and the crown on it. Haptic feedback to the surgeon in real time can decrease dependence on the surgeon's skill and experience for accurate implant positioning and increase the overall safety of the procedure. The develope...
Selenium doped calcium phosphate biomimetic coating on Ti6Al4V orthopedic implant material for anti-cancer and anti-bacterial purposes
Yılmaz, Bengi; Evis, Zafer; Banerjee, Sreeparna; Department of Biomedical Engineering (2014)
In order to prevent recurrent osteosarcoma in patients undergone surgical resection for implant insertion and infection around implant site, which is a very common complication after surgery, it is very important to functionalize the surface. In this study, to combine the effective antioxidant and potential anti-cancer and anti-bacterial properties of selenium with the high biocompatibility and bioactivity of hydroxyapatite, selenium was added to the structure of hydroxyapatite via biomimetic method and coa...
Metabolomics analysis of iPSCs derived organoids
Sarı , Vedat; Koçak , Gamze; Reçber, Tuba; Karakülah , Gökhan; Utine , Canan Aslı; Nemutlu , Emirhan; Güven, Sinan (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10)
Regenerative medicine is focused on functional restoration of a particular tissue and organs. Stem cell based miniaturized heterogenous cellular clusters named organoids, exhibit features of organ functionality, self-organization, multicellularity, and utility. Induced pluripotent stem cells (iPSCs), have great potential to develop organoids of specific tissues and utilized in regenerative medicine. Organoid technologies have revolutionized the approach to human development and diseases, providing outstandi...
Immobilization of heparin on chitosan-grafted polyurethane films to enhance anti-adhesive and antibacterial properties
Kara, Filiz; AKSOY, EDA AYŞE; ÇALAMAK, SEMİH; Hasırcı, Nesrin; AKSOY, SERPİL (2016-01-01)
Infections caused by bacteria adhering to implant surfaces are one of the main reasons for the failure of the implants. In this study, polyurethane (PU), which is the most commonly used polymer in the production of medical devices, was synthesized and surfaces of polyurethane films were modified by chitosan (CH) grafting and heparin (Hep) immobilization in order to enhance anti-adhesiveness and antibacterial properties. Functional groups present on the surface, topographical shapes, and free energies of the...
Citation Formats
E. Uslu and B. Ercan, “Anodized Tantalum Surfaces for Orthopedic Applications,” presented at the 19th International Metallurgy & Materials Congress, 2018, Accessed: 00, 2021. [Online]. Available: