FGX (frequentist gene expression index) for Affymetrix arrays under non-normality assumption

2008-06-01

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FGX: a frequentist gene expression index for Affymetrix arrays
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We consider a new frequentist gene expression index for Affymetrix oligonucleotide DNA arrays, using a similar probe intensity model as suggested by Hein and others (2005), called the Bayesian gene expression index (BGX). According to this model, the perfect match and mismatch values are assumed to be correlated as a result of sharing a common gene expression signal. Rather than a Bayesian approach, we develop a maximum likelihood algorithm for estimating the underlying common signal. In this way, estimatio...
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FGX implementation in two case studies
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Citation Formats
V. Purutçuoğlu Gazi, “FGX (frequentist gene expression index) for Affymetrix arrays under non-normality assumption,” 2008, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/79171.