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Ancient genomics in Anatolia: challenges and opportunities
Date
2019-10-19
Author
Somel, Mehmet
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The increasing availability of ancient genomes has been accelerating studies in a number of fields, including human history, molecular evolution, and conservation biology. The METU/Hacettepe Ancient DNA Group has been contributing to these endeavors by producing and analyzing ancient DNA data from archaeological human and animal remains of Anatolian origin, from the last 10,000 years. However, the temperate climate conditions across most parts of Anatolia drive rapid DNA degradation, and most biological material examined harbor only trace amounts of endogenous DNA (median <1% of shotgun sequenced molecules). Hence, the genomes produced are typically only partial (median <0.1x coverage). In this talk, I will discuss different computational approaches to overcome the limitations posed by extremely low coverage data. I will further share examples of new genetic-based insights into Anatolian human societies from 10,000 years ago, including their regional movements and social traditions.
URI
https://www.ibg.edu.tr/Uploads/event_image/hibit_abstractbook.pdf
https://hdl.handle.net/11511/79637
Conference Name
THE 12TH INTERNATIONAL SYMPOSIUM ON HEALTH INFORMATICS AND BIOINFORMATICS, 17 - 19 Ekim 2019
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M. Somel, “Ancient genomics in Anatolia: challenges and opportunities,” presented at the THE 12TH INTERNATIONAL SYMPOSIUM ON HEALTH INFORMATICS AND BIOINFORMATICS, 17 - 19 Ekim 2019, 2019, Accessed: 00, 2021. [Online]. Available: https://www.ibg.edu.tr/Uploads/event_image/hibit_abstractbook.pdf.
