Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Open Access Guideline
Open Access Guideline
Postgraduate Thesis Guideline
Postgraduate Thesis Guideline
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
Development and in vitro characterization of levodopa and glutathione co-loaded liposomal formulations
Date
2017-05-14
Author
Gurturk, Zeynep
Tezcaner, Ayşen
Dalgıç, Ali Deniz
Korkmaz, Seval
Keskin, Dilek
Metadata
Show full item record
Item Usage Stats
151
views
0
downloads
Cite This
URI
https://hdl.handle.net/11511/80811
Collections
Unverified, Conference / Seminar
Suggestions
OpenMETU
Core
Development and analysis of controlled release polymeric rods containing vancomycin
Tağıt, Oya; Hasırcı, Vasıf Nejat; Department of Biotechnology (2005)
Antibiotic use is a vital method for the treatment of most diseases involving bacterial infections. Unfortunately, in certain cases these agents are not effective in treatments against diseases for either some limitation in antibiotic usage because of the side effects or some distribution problems caused by physiological or pathological barriers in the body. Such problems are thought to be minimized by development of controlled release systems which involve implantation of antibiotic loaded polymeric system...
Development and preclinical evaluation of virus-like particle vaccine against COVID-19 infection
YILMAZ, İSMAİL CEM; et. al. (2021-09-01)
Background Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes the development and immunogenicity of SARS-CoV-2 VLP vaccine that incorporates the four structural proteins of SARS-CoV-2. Methods VLPs were generated in transiently transfected HEK293 cells, purified by multimodal chromatography, and characterized by tunable-resistive pulse sensing, AFM, SEM, and TEM. Immunoblotting studies verified the prot...
Development and investigation of etoposide resistance in MCF-7 Breast cancer cell line
Kaplan, Esra; Gündüz, Ufuk; Department of Biology (2010)
Failure of chemotherapy in cancer patients because of development of drug resistance is a major problem. Alterations of DNA repair mechanisms and drug targets are among the important resistance mechanisms which are developed against topoisomerase II inhibitors etoposide and doxorubicin. Modifications in the expression levels of mismatch repair (MMR) genes due to resistance to topoisomerase II inhibitors are involved in breast cancer. In this study, etoposide resistant sublines were developed from MCF7 breas...
Development and Characterization of PEG-B-PCL Micelles Carrying Anticancer Agents
Işık, Gülhan; Tezcaner, Ayşen; Hasırcı, Nesrin; Department of Biotechnology (2022-2-9)
Cancer is a disease that decreases the quality of life. Many cancer drugs are either toxic or not effective due to their fast removal by reticuloendothelial system. Therefore, nano-sized drug delivery systems, especially the ones carrying the drugs directly to tumor, gained attention in the last decades. The aim of the study was to prepare nano-sized drug carrying micelles (drug conjugated and drug loaded) from methoxy polyethylene glycol-block-polycaprolactone (mPEG-b-PCL). In order to conjugate drugs, mPE...
Development of an experimental recombinant vaccine formulation composed of LKTA from Mannheimia Haemolytica A1 and P31 and LPPB from Histophilus Somni 8025 against Hovine Respiratory Disease
Türkmen, Nazlı Hilal; Özcengiz, Gülay; Department of Molecular Biology and Genetics (2020-9)
Two major bacterial pathogens of Bovine Respiratory Disease (BRD), Mannheimia haemolytica and Histophilus somni are Gram-negative, opportunistic bacteria that live in upper respiratory tracts of ruminants commensally. The one of the most important virulence factor of M. haemolytica, leukotoxin, is responsible for lung colonization and establishment of infection. On the other hand, H. somni OMPs have a significant contribution to the pathogenicity of the organism. As the disease results in a destroyed animal...
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
Z. Gurturk, A. Tezcaner, A. D. Dalgıç, S. Korkmaz, and D. Keskin, “Development and in vitro characterization of levodopa and glutathione co-loaded liposomal formulations,” 2017, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/80811.