Colicinogeny, lipopolysaccharide and outer membrane protein profiles of multi-drug resistant Salmonella typhimurium isolates from Turkey

Date

2002-01-01

Author

İçgen, Bülent
Özcengiz, Gülay
Gültekin, Güzin Candan

Metadata

Show full item record

Item Usage Stats

122
views

0
downloads

A total of 259 clinical isolates of non-repetitive non-typhi salmonellae (NTS) were previously examined for their antibiotic resistance patterns and plasmid contents. Multi-drug resistant strains comprised 19.3% (50/259) of the isolates and almost all were Salmonella typhimurium. In the present study, 35 of these multi-drug resistant S. typhimurium isolates were further characterized for colicinogeny, lipopolysaccharide (LPS) and outer membrane protein (OMP) profiles. Fourteen of the 35 (40%) isolates were found to be colicin producers. All isolates showed smooth-type LPS. In 26 of the (74.3%) isolates, OMPs of 30.6 and 34.6 kDa were observed whereas three (8.6%) of them were found to carry only a 30.6 kDa protein and six (17.1%) carried 27.2, 30.6 and 34.6 kDa proteins. There was no direct correlation between the plasmid contents, antibiotic resistance patterns, colicinogeny, LPS and OMP profiles of the isolates.

Subject Keywords

Salmonella, Colicin Production, LPS, OMP, Plasmid

URI

https://journals.tubitak.gov.tr/medical/abstract.htm?id=5893
https://hdl.handle.net/11511/85190

Journal

Turkish Journal Of Medical Sciences

Collections

Department of Environmental Engineering, Article

Suggestions

OpenMETU
Core

Enzymatic extraction of activated sludge extracellular polymers and implications on bioflocculation Sesay, Ml; Özcengiz, Gülay; Sanin, Faika Dilek (Elsevier BV, 2006-04-01) This study examines enzyme hydrolysis, a mild, effective, but a rarely used method of extracellular polymer extraction, in removing polymers from mixed culture activated sludge flocs. Two carbohydrate specific enzymes (a-amylase and cellulase) and a protein specific enzyme (proteinase) are used during the study. First, the kinetic aspect is investigated, then enzyme dose optimization is carried out on laboratory grown activated sludge samples cultured at solids retention times (SRT) of 4 and 20 days. A more...
Enantioselective synthesis of new chiral 2-aziridinyl phosphonates and studies of their biological activities Doğan, Özdemir; Beksultanova, Nurzhan; ALTANLAR, NURTEN; Simsek, Duygu; KARABIYIK, HASAN (2017-02-15) A new series of chiral aziridinyl phosphonates has been synthesized and evaluated for antibacterial and antifungal activities. For the synthesis, a Gabriel-Cromwell reaction was used to form aziridinyl phosphonates in 52-83% yield. In order to evaluate antibacterial and antifungal activities, MIC values were measured. Although most of the compounds showed insignificant activity, two of them provided low to moderate antifungal activity.
Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation Kayaoğlu, Başak; Yilmaz, Naz Surucu; Charbonnier, Louis Marie; Geckin, Busranur; Akcay, Arzu; Eltan, Sevgi Bilgic; Ozturk, Gulyuz; ÖZEN, AHMET OĞUZHAN; Karakoc-Aydiner, Elif; Chatila, Talal A.; Gürsel, Mayda (2021-01-01) Purpose Patients with heterozygous gain-of-function (GOF) mutations in STAT1 frequently exhibit chronic mucocutaneous candidiasis (CMC), immunodeficiency and autoimmune manifestations. Several treatment options including targeted therapies and hematopoietic stem cell transplantation (HSCT) are available for STAT1 GOF patients but modalities and outcomes are not well established. Herein, we aimed to unravel the effect of ruxolitinib as a bridge therapy in a patient with sporadic STAT1 T385M mutation to manag...
Multiple drug resistance patterns and plasmid profiles of non-typhi salmonellae in Turkey Yildirmak, T; Yazgan, A; Özcengiz, Gülay (1998-10-01) A total of 259 clinical isolates of nonrepetitive non-typhi salmonellae (NTS) were examined for antibiotic resistance patterns and plasmid content. The antibiotics used were amoxicillin-clavulanic acid (AMC), ampicillin (AM), aztreonam (ATM), carbenicillin (CB), cefixime (CFM), cefotaxime (CTX), cefoxitin (FOX), ceftazidime (CAZ), ceftriaxone (CRO), chloramphenicol (C), ciprofloxacin (CIP), gentamicin (GM), imipenem (IPM), ofloxacin (OFX), tetracycline (TE), trimethoprim-sulfomethoxazole (SXT). Multi-drug r...
VanA-Type MRSA (VRSA) Emerged in Surface Waters İçgen, Bülent (Springer Science and Business Media LLC, 2016-09-01) Due to the widespread occurrence of mecA-encoded methicillin resistance in Staphylococcus aureus (MRSA), treatment of staphylococcal infections is shifted to glycopeptide antibiotics like vancomycin and teicoplanin. The selective pressure of glycopeptides has eventually led to the emergence of staphylococci with increased resistance. Of great concern is vanA-encoded high level vancomycin and teicoplanin resistance in MRSA (VRSA). Therefore, this study aimed at investigating the occurrence of VRSA in surface...

Citation Formats

B. İçgen, G. Özcengiz, and G. C. Gültekin, “Colicinogeny, lipopolysaccharide and outer membrane protein profiles of multi-drug resistant Salmonella typhimurium isolates from Turkey,” Turkish Journal Of Medical Sciences, pp. 483–486, 2002, Accessed: 00, 2021. [Online]. Available: https://journals.tubitak.gov.tr/medical/abstract.htm?id=5893.