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Recent Submissions

Insight into greenhouse gas emission in freshwater aquaculture ponds in Jiangsu Province: Variation due to species used and ponds management practice Li, Yifan; Wang, Hongyu; Zeng, Qingfei; Jeppesen, Erik; Gu, Xiaohong; Yan, Jie (2026-02-01) Aquaculture ponds have emerged as a significant contributor to greenhouse gas (GHG) emissions. We measured methane (CH4), carbon dioxide (CO2), and nitrous oxide (N2O) emissions in ponds, all located in Jiangsu Province, w...
Api-TRACE: A system for honey bee tracking in a constrained environment to study bee learning process and the effect of lithium on learning Erdem, Babür; Ince, Ayben; SEVİN, SEDAT; Arslan, Okan Can; Gözen, Ayşe Gül; Giray, Tugrul; Alemdar, Hande (2026-02-01) Learning is an adaptive behavior that improves the performance of bees in foraging, dance communication, predator avoidance, and other tasks. Any deficiencies in learning could be detrimental to the long-term survival of t...
Thermal power plant proximity alters Olive composition and induces cytotoxicity in human cells Gürbüz, Esra; Aksoy, Emre; Sandallı, Aytül; BİLGİLİ TETİKOĞLU, FUNDA; Şeker, Enes; Kıran, Naciye Nisa; Tetikoğlu, Sinan; MURATOĞLU, HACER; Kaya, Muhammed Fatih; AKYÜZ TURUMTAY, EMİNE; Çelik Uzuner, Selcen (2025-12-01) Thermal power plants (TPPs) are essential for meeting increasing energy demands, but they also pose significant environmental and health risks. The Yatağan TPP in Türkiye is located near agricultural and residential areas,...
A small molecule enhances arrestin-3 binding to the β2-adrenergic receptor Kurt, Han; Akyol, Ali; Son, Çağdaş Devrim; Zheng, Chen; Gado, Irene; Meli, Massimiliano; Ferrandi, Erica Elisa; Bassanini, Ivan; Vasile, Francesca; Gurevich, Vsevolod V.; Nebol, Aylin; Cagavi, Esra; Morra, Giulia; Sensoy, Ozge (2025-12-01) Excessive signaling by various GPCRs underlies a variety of human disorders. Suppression of GPCRs by “enhanced” arrestin mutants was proposed as therapy. We hypothesized that GPCR binding of endogenous arrestins can be inc...
3'UTR RNA editing driven by ADAR1 modulates MDM2 expression in breast cancer cells Almeric, Elanur; Karagozoglu, Deniz; Cicek, Mustafa; Dioken, Didem Naz; Tac, Huseyin Avni; Cicek, Esra; Kirim, Busra Aytul; Gurcuoglu, Irmak; Sezerman, Osman Ugur; Ozlu, Nurhan; Erson Bensan, Ayşe Elif (2025-12-01) Epitranscriptomic changes in the transcripts of cancer related genes could modulate protein levels. RNA editing, particularly A-to-I(G) editing catalyzed by ADAR1, has been implicated in cancer progression. RNA editing eve...
Genome-wide association study of common bean (Phaseolus vulgaris L.) unveils novel loci governing root-to-seed zinc allocation ALTAF, MUHAMMAD TANVEER; Nadeem, Muhammad Azhar; Ayten, Sefa; Aksoy, Emre; Mansoor, Sheikh; Karunathilake, E.M.B.M.; Chung, Yong Suk; Baloch, Faheem Shehzad (2025-12-01) Micronutrient malnutrition is a global health concern, highlighting the importance of essential micronutrients like zinc in human diet, and enhancing zinc concentration in staple crops like common beans is a promising stra...
Association of nesting Otus scops (Eurasian Scops Owl) with Xerotyphlops vermicularis (worm snake) in Türkiye Gocer, Elif; Johnson, David H.; Bilgin, Cemal Can; Vrezec, Al (2025-11-24) We report the discovery of a novel relationship between Otus scops (Eurasian Scops Owl) and Xerotyphlops vermicularis (worm snake) found during systematic nest box inspections spanning 6 breeding seasons in central T & uum...
Addressing the specific roles of histone modifications in transcriptional repression. Hedehus, Lin; Mas, Aina M; Alpsoy, Aktan; Armstrong, Robin L; Koche, Richard; Tatar, Tülin; Wang, Hua; Helin, Kristian (2025-11-22) Our understanding of epigenetic processes is based on the hypothesis that individual posttranslational modifications of DNA and histones, or combina- tions thereof, function to direct unique downstream effects on transcrip...
Climate and habitat types drive avian communities of the Anatolian Diagonal Gurol, Ilgin Ertan; Ambarlı, Didem; Zeydanli, Ugur (2025-11-03) Avian diversity is experiencing alarming declines across the globe. Still, several biodiversity hotspots remain to be studied in terms of avian communities. At the convergence of three global biodiversity hotspots lies the...
Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3 Alpsoy, Aktan; Ipsaro, Jonathan J.; Skopelitis, Damianos; Pal, Sujay; Chung, Frank S.; Carpenter, Shannon; Desmarais, John J.; Wu, Xiaoli S.; Chang, Kenneth; DiMare, Matthew T.; Harten, Erin; Bergman, Staci; Kinney, Justin B.; Engelman, Jeffrey A.; Bhang, Hyo-Eun C.; Joshua-Tor, Leemor; Vakoc, Christopher R. (2025-11-01) The transcription factor POU2F3 defines the identity of tuft cells and underlies a distinct molecular subtype of small cell lung cancer (SCLC). Although POU2F3 is considered undruggable, its activity critically depends on ...
Diverse Foraging in Small-Bodied Fishes: Effects on Water Quality and Submerged Macrophytes in Shallow Subtropical Lake Ecosystems Guo, Chao; Li, Wei; Hansen, Adam G.; Li, Shiqi; Ke, Jie; Jeppesen, Erik; Liao, Chuansong; Yuan, Jing; Zhang, Tanglin; Guo, Chuanbo; Liu, Jiashou (2025-11-01) The proliferation of small-bodied fishes and their foraging effects within food webs can limit the growth of submerged macrophytes and degrade water quality in shallow lake ecosystems. The foraging habits of small-bodied f...
Single-cell transcriptional profiling in Arabidopsis root exposed to boron toxicity at seedling stages Kayıhan, Ceyhun; Kocakaya, Ebru; KAYMAZ, YASİN; Yilmaz, Hikmet; Ünal, Halis Batuhan; Yaprak, Oğuzhan; Aksoy, Emre; Karagöz, Dilara Sedef (2025-10-01) Cell-specific transcriptional responses to environmental stimuli are yet to be fully characterized. Single-cell sequencing technology allows us to analyze different cell types under different conditions. Here, high-through...
Intraguild Predation Is Insufficiently Mitigated by Complex-Structured Aquatic Vegetation Su, Yaling; He, Hu; Li, Kuanyi; Liu, Zhengwen; Jeppesen, Erik (2025-10-01) Intraguild predation (IGP) occurs when one predator species consumes another species with whom it also competes for shared prey. IGP is widely believed to reduce prey suppression. In terrestrial ecosystems, structurally co...
Phosphorylation of SNAP-25 at Ser187 is enhanced following its cleavage by Botulinum Neurotoxin Serotype A, promoting the dominant-negative effect of the resulting fragment Koc, Dilara; Ezgin, Sena; Kavakli, Ebru; Kota, Krishna P.; Sen, Edanur; Mahone, Christopher; Palko, Mary Ellen; Cazares, Lisa H.; Can, Tolga; Tessarollo, Lino; Bavari, Sina; Marıon, Antoıne; Kiriş, Erkan (2025-10-01) Botulinum Neurotoxin Serotype A (BoNT/A), responsible for most human botulism cases, inhibits neurotransmitter release by cleaving the target protein SNAP-25. Previous literature demonstrated that BoNT/A mediated cleavage ...
Dissecting Trends in the Latitudinal Diversity Gradient of Benthic Macroinvertebrates in Freshwater Lakes Across Scales He, Hu; Zhang, You; Li, Yan; Peng, Kai; Rutter, Robert P.; Jyväsjärvi, Jussi; Hämäläinen, Heikki; Ntislidou, Chrysoula; Wang, Jianjun; Zhang, Min; Li, Kuanyi; Liu, Zhengwen; Johansson, Liselotte S.; Søndergaard, Martin; Cai, Yongjiu; Wang, Haijun; Jeppesen, Erik; Chase, Jonathan M. (2025-10-01) The latitudinal diversity gradient is one of the most striking biogeographical patterns on Earth and typically reveals increases in species richness from the poles towards the tropics. However, the latitudinal diversity pa...
E2-regulated transcriptome complexity revealed by long-read direct RNA sequencing: from isoform discovery to truncated proteins. Dioken, Didem Naz; Ozgul, Ibrahim; Yilmazbilek, Irem; Almeric, Elanur; Eroglu, Irem Cemile; Cicek, Mustafa; Yilmaz, Utku Cem; Karagozoglu, Deniz; Cicek, Esra; Karaca, Ezgi; Can, Tolga; Erson Bensan, Ayşe Elif (2025-09-18)
Low plasticity in coumarin-based Fe acquisition restricts species to soils with narrow pH ranges Gora, Desara; Mandebere, Deon; Eroğlu, Seçkin (2025-09-18) AimsIron (Fe) deficiency severely limits crop growth in calcareous soils. Research into responses to Fe deficiency has focused chiefly on crops and model plants. Wild plants may exhibit natural variations in Fe uptake stra...
SET domain containing 3 (SETD3) interacts with bromodomain-containing protein 2 (BRD2) and coordinates its chromatin association in mouse embryonic stem cells. Sezginmert, Dersu; Guven, Gozde; Alganatay, Ceren; Ak, Deniz; Terzi Çizmecioğlu, Nihal (2025-09-13)
Stakeholder Perspectives on Pondscapes: A Multinational Analysis Using Storylines and the Nature Futures Framework Rashidi, Parinaz; Patil, Sopan; Jan, Kuiper; Tenbrink, Thora; Perrin, Jacques-Aristide; Robin, Joel; Brucet, Sandra; Lemmens, Pieter; Meerhoff, Mariana; Mehner, Thomas; Benejam, Lluis; Oertli, Beat; Beklioğlu, Meryem; Davidson, Thomas A.; Boissezon, Aurelie; Biggs, Jeremy; Nicolet, Pascale; Williams, Penny; Wijns, Robby; Rosa, Isabel (2025-09-01)
The Input of Terrestrial Dissolved Organic Carbon Enhanced Bacteria Growth Efficiency on Phytoplankton-DOC and Indigenous Lake DOC: A Microcosm Study Jin, Zong’an; Zhang, Huiping; Liu, Zhengwen; Jeppesen, Erik; Gao, Jian; Tang, Yali (2025-09-01) As a consequence of global climate change, lakes are increasingly receiving terrestrial dissolved organic carbon (DOC), which serves as a key substrate for microbial metabolism and fuels bacterial production (BP). However,...

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