Department of Biology

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Severcan, Feride (165)
Adalı, Orhan (101)
Doğan, Musa (97)
Öktem, Hüseyin Avni (91)
Beklioğlu, Meryem (83)

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General Medicine (123)
Biochemistry (111)
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Ecology, Evolution, Behavior and Systematics (56)
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1971 - 1979 (11)
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2020 - 2023 (112)

Recent Submissions

Archaeogenomic analysis of genetic and cultural interactions in Neolithic Anatolian societies (NEOGENE)
Somel, Mehmet; Atakuman, Çiğdem; Sürer, Elif; Erdal, Yılmaz Selim; Özer, Füsun(2023)
The Neolithic Transition in the Near East (c.10,000-6,000 BC) was a period of singular sociocultural change, when societies adopted sedentary life and agriculture for the first time in human history. This project will join...
Network of Leading European AQUAtic MesoCOSM Facilities Connecting Mountains to Oceans from the Arctic to the Mediterranean (AQUACOSM)
Beklioğlu, Meryem(2021-8-31)
Experimentation in mesocosms is arguably the single most powerful approach to obtain a mechanistic quantitative understanding of ecosystem-level impacts of stressors in complex systems, especially when embedded in long-ter...
Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes
Yaka, Reyhan; et. al. (2021-06-01)
Inhibition of Wnt signalling by Notch via two distinct mechanisms.
Acar, Ahmet; Hidalgo-Sastre, Ana; Leverentz, Michael K; Mills, Christopher G; Woodcock, Simon; Baron, Martin; Collu, Giovanna M; Brennan, Keith (2021-04-27)
INVESTIGATION OF THE EFFECTS OF NUTRIENT RESTRICTION ON LYSOSOMAL TRAFFICKING IN COLORECTAL CANCER CELLS
Hüsnügil, Hepşen Hazal; Güleç, Aliye Ezgi; Oral, Göksu; Erson Bensan, Ayşe Elif; Banerjee, Sreeparna (2021-04-10)
Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview.
Di Fiore, Riccardo; Suleiman, Sherif; Pentimalli, Francesca; O’toole, Sharon A.; O’leary, John J.; Ward, Mark P.; Conlon, Neil T.; Sabol, Maja; Ozretić, Petar; Erson Bensan, Ayşe Elif; Reed, Nicholas; Giordano, Antonio; Herrington, C. Simon; Calleja-Agius, Jean (2021-04-07)
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.Gynecological cancers pose an important public health issue, with a high incidence among women of all ages. Gynecological cancers such as malignant germ-cell tumors,...
Convolutional Neural Networks for Classification of Colorectal Cancer on Whole Slide Images
Temena, Mehmet Arda; Isildak, Ulas; Acar, Ahmet (2021-03-27)
Demography of swordfish (Xiphias gladius Linneus) populations from the coasts of Turkey, based on mitochondrial DNA and microsatellites
Yuncu, Eren; Acan, Sinan Can; ONAR, Vedat; Karakulak, F. Saadet; GÖKOĞLU, MEHMET; Alicli, Turgut Zahit; Chiriboga, Fidel; Togan, İnci Zehra; Ozer, Fusun (2021-03-01)
The genetic diversity of the Mediterranean swordfish (Xiphias gladius Linneus) has not been explored extensively at its easternmost range so far. In this study, modern X. gladius samples from the eastern part of the Medite...
Million-year-old DNA sheds light on the genomic history of mammoths
van der Valk, Tom; et. al. (Springer Science and Business Media LLC, 2021-2-17)
Temporal genomic data hold great potential for studying evolutionary processes such as speciation. However, sampling across speciation events would, in many cases, require genomic time series that stretch well back into th...
Arid4b alters cell cycle and cell death dynamics during mouse embryonic stem cell differentiation.
Güven, Gözde; Terzi Çizmecioğlu, Nihal (2021-02-09)
Cell division and death play an important role in embryonic development. Cell specialization is accompanied with slow proliferation and quiescence. Cell death is important for morphogenesis. Gene expression changes during ...
Identification of Potential Therapeutic Genes and Pathways in Phytoestrogen Emodin Treated Breast Cancer Cell Lines via Network Biology Approaches
Sakalli-Tecim, Elif; Uyar-Arpaci, Pembegul; Güray, Nülüfer Tülün (2021-02-01)
Phytoestrogens have been investigated for their potential anti-tumorigenic effects in various cancers including breast cancer. Emodin being a phytoestrogen shows anti-carcinogenic properties especially in estrogen receptor...
Nutrient Loading, Temperature and Heat Wave Effects on Nutrients, Oxygen and Metabolism in Shallow Lake Mesocosms Pre-Adapted for 11 Years
Jeppesen, Erik; Audet, Joachim; Davidson, Thomas A.; Neif, Erika M.; Cao, Yu; Filiz, Nur; Lauridsen, Torben L.; Larsen, Soren E.; Beklioğlu, Meryem; Sh, Tserenpil; Sondergaard, Martin (2021-01-01)
Global changes (e.g., warming and population growth) affect nutrient loadings and temperatures, but global warming also results in more frequent extreme events, such as heat waves. Using data from the world's longest-runni...
Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation
Kayaoğlu, Başak; Kasap, Nurhan; Yilmaz, Naz Surucu; Charbonnier, Louis Marie; Geckin, Busranur; Akcay, Arzu; Eltan, Sevgi Bilgic; Ozturk, Gulyuz; ÖZEN, AHMET OĞUZHAN; Karakoc-Aydiner, Elif; Chatila, Talal A.; Gürsel, Mayda; BARIŞ, SAFA (2021-01-01)
Purpose Patients with heterozygous gain-of-function (GOF) mutations in STAT1 frequently exhibit chronic mucocutaneous candidiasis (CMC), immunodeficiency and autoimmune manifestations. Several treatment options including t...
Vitamin E Derivative with Modified Side Chain Induced Apoptosis by Modulating the Cellular Lipids and Membrane Dynamics in MCF7 Cells
Gok, Seher; Kuzmenko, Oleksandr; Babinskyi, Andrii; Severcan, Feride (Springer Science and Business Media LLC, 2021-01-01)
The vitamin E derivative with side chain modification (TC6OAc) has been shown to possess anticancer activity in our earlier in vivo studies. It was hypothesized that, as Vitamin E (VE) and VE derivative are fat soluble lip...
Human population dynamics and Yersinia pestis in ancient northeast Asia
Kilinc, Gulsah Merve; et. al. (2021-01-01)
We present genome-wide data from 40 individuals dating to c.16,900 to 550 years ago in northeast Asia. We describe hitherto unknown gene flow and admixture events in the region, revealing a complex population history. Whil...
Allergen fragrance molecules: a potential relief for COVID-19
Aydin, Asli Deniz; Altinel, Faruk; Erdogmus, Hueseyin; Son, Çağdaş Devrim (2021-01-01)
BackgroundThe latest coronavirus SARS-CoV-2, discovered in China and rapidly spread Worldwide. COVID-19 affected millions of people and killed hundreds of thousands worldwide. There are many ongoing studies investigating d...
Ancient genomics in Neolithic Central Anatolia and Çatalhöyük
Yaka, Reyhan; Doğu, Ayça; Kaptan, Damla; Dağtaş, Nihan Dilşad; Chyleński, Maciej; Vural, Kıvılcım Başak; Altınışık, Nefize Ezgi; Mapelli, Igor; Koptekin, Dilek; Karamurat, Cansu; Gemici, Hasan Can; Yorulmaz, Sevgi; Lagerholm, Vendela Kempe; Fer, Evrim; Işıldak, Ulaş; Ghalichi, Ayshin; Kılınç, Gülşah Merve; Mazzucato, Camilla; Juras, Anna; Marciniak, Arkadiusz; Larsen, Clark S.; Pilloud, Marin; Haddow, Scott D.; Knüsel, Christopher J.; Togan, İnci; Götherström, Anders; Erdal, Yılmaz Selim; Sürer, Elif; Özer, Füsun; Atakuman, Çiğdem; Somel, Mehmet (British Institute of Archaeology at Ankara, 2021-01-01)
Over multiple millennia, from the earliest traces of long-term occupation of camp sites (ca 20,000 BC) to the development of full-scale farming (ca 8000–6000 BC), the Neolithic transition in southwest Asia gradually shaped...
Proteomic Analysis of a hom-Disrupted, Cephamycin C Overproducing Streptomyces clavuligerus
Unsaldi, Eser; KURT KIZILDOĞAN, ASLIHAN; ÖZCAN, SERVET; Becher, Dorte; Voigt, Birgit; Aktas, Caner; Özcengiz, Gülay (2021-01-01)
Background: Streptomyces clavuligerus is prolific producer of cephamycin C, a medically important antibiotic. In our former study, cephamycin C titer was 2-fold improved by disrupting homoserine dehydrogenase (hom) gene of...
The host musselSinanodonta woodianaalleviates negative effects of a small omnivorous fish (Acheilognathus macropterus) on water quality: A mesocosm experiment
Yu, Jinlei; Xia, Manli; He, Hu; Jeppesen, Erik; Guan, Baohua; Ren, Ze; Elser, James J.; Liu, Zhengwen (University of Chicago Press, 2020-12-01)
Omnivorous fishes are prevalent in warm waters and may have strong impacts on water quality by excreting nutrients and reducing periphyton biomass. However, most studies have focused on large-sized species and overlooked t...
Impact of Nutrients, Temperatures, and a Heat Wave on Zooplankton Community Structure: An Experimental Approach
Iskin, Ugur; Filiz, Nur; Cao, Yu; Neif, Erika M.; Oglu, Burak; Lauridsen, Torben L.; Davidson, Thomas A.; Sondergaard, Martin; Tavsanoglu, Ulku Nihan; Beklioğlu, Meryem; Jeppesen, Erik (MDPI AG, 2020-12-01)
Shallow lakes are globally the most numerous water bodies and are sensitive to external perturbations, including eutrophication and climate change, which threaten their functioning. Extreme events, such as heat waves (HWs)...
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