Department of Biology

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Severcan, Feride (174)
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Recent Submissions

Archaeogenomic analysis of genetic and cultural interactions in Neolithic Anatolian societies (NEOGENE)
Somel, Mehmet; Atakuman, Çiğdem; Sürer, Elif(2023)
The Neolithic Transition in the Near East (c.10,000-6,000 BC) was a period of singular sociocultural change, when societies adopted sedentary life and agriculture for the first time in human history. This project will join...
New insights on commemoration of the dead through mortuary and architectural use of pigments at Neolithic Çatalhöyük, Turkey
Schotsmans, E.M.J.; Busacca, G.; Lin, S.C.; Vasić, M.; Lingle, A.M.; Veropoulidou, R.; Mazzucato, C.; Tibbetts, B.; Haddow, S.D.; Somel, Mehmet; Toksoy-Köksal, F.; Knüsel, C.J.; Milella, M. (2022-12-01)
The cultural use of pigments in human societies is associated with ritual activities and the creation of social memory. Neolithic Çatalhöyük (Turkey, 7100–5950 cal BC) provides a unique case study for the exploration of li...
Rapid diagnosis of malignant pleural mesothelioma and its discrimination from lung cancer and benign exudative effusions using blood serum
Yonar, Dilek; Severcan, Mete; Gurbanov, Rafig; Sandal, Abdulsamet; Yilmaz, Ulku; Emri, Salih; Severcan, Feride (2022-10-01)
© 2022Malignant pleural mesothelioma (MPM), an aggressive cancer associated with exposure to fibrous minerals, can only be diagnosed in the advanced stage because its early symptoms are also connected with other respirator...
World Natural Heritage Nominations: Potential Sites of Turkey and Difficulties of Nomination
Kaya, Zeki (Koç University Press, 2022-09-01)
Effects of a microplastic mixture differ across trophic levels and taxa in a freshwater food web: In situ mesocosm experiment
Yıldız, Dilvin; Yalçın, Gülce; Jovanović, Boris; Boukal, David S.; Vebrová, Lucie; Riha, Derya; Stanković, Jelena; Savić-Zdraković, Dimitrija; Metin, Melisa; Akyürek, Yasmin Naz; Balkanlı, Deniz; Filiz, Nur; Milošević, Djuradj; Feuchtmayr, Heidrun; Richardson, Jessica A.; Beklioğlu, Meryem (2022-08-25)
© 2022The ubiquitous presence of microplastics (MP) in aquatic ecosystems can affect organisms and communities in multiple ways. While MP research on aquatic organisms has primarily focused on marine ecosystems and laborat...
The ancient DNA and archaeobotanical analysis suggest cultivation of Triticum aestivum subsp. spelta at Yumuktepe and Yenikapi Pottery Neolithic sites in Turkey
Degirmenci, Funda O.; ULAŞ, BURHAN; Kansu, Cigdem; Ulug, Asiye; Caneva, Isabella; Asal, Rahmi; Kaya, Zeki (2022-08-01)
Archaeobotanical materials subject to aDNA analysis were recovered from Yumuktepe and Yenikapi, two important archaeological sites in Anatolia and date back to the Pottery Neolithic Period i.e., 7th millennium BC. Many cha...
ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2
Huebner, Kerstin; et. al. (2022-08-01)
In cancer, the activating transcription factor 2 (ATF2) has pleiotropic functions in cellular responses to growth stimuli, damage, or inflammation. Due to only limited studies, the significance of ATF2 in colorectal cancer...
Structural and functional evaluation mammalian and plant lipoxygenases upon association with nanodics as membrane mimetics.
Ulusan, Sinem; Sheraj, Ilir; Stehling, Sabine; Ivanov, Igor; Das, Aditi; Kühn, Hartmut; Banerjee, Sreeparna (2022-07-08)
Capturing Wheat Phenotypes at the Genome Level
Hussaın, Babar; et. al. (2022-07-04)
Recent technological advances in next-generation sequencing (NGS) technologies have dramatically reduced the cost of DNA sequencing, allowing species with large and complex genomes to be sequenced. Although bread wheat (Tr...
Editorial: Epithelial to Mesenchymal Plasticity in Colorectal Cancer
Bocci, Federico; Schneider-Stock, Regine; Banerjee, Sreeparna (2022-06-23)
UNESCO Dünya Doğal Miras Alanı Başvuru Süreci, Türkiye'nin Unesco Dünya Doğal Miras Alan Potansiyeli ve Başvuru Zorlukları
Kaya, Zeki (Koc University Press, 2022-06-01)
Setd3-dependent gene expression changes during endoderm differentiation of mouse embryonic stem cells
Balbaşı, Emre; Terzi Çizmecioğlu, Nihal (2022-05-28)
Freshwater salinisation: a research agenda for a saltier world
Cunillera-Montcusí, David; Beklioğlu, Meryem; Cañedo-Argüelles, Miguel; Jeppesen, Erik; Ptacnik, Robert; Amorim, Cihelio A.; Arnott, Shelley E.; Berger, Stella A.; Brucet, Sandra; Dugan, Hilary A.; Gerhard, Miriam; Horváth, Zsófia; Langenheder, Silke; Nejstgaard, Jens C.; Reinikainen, Marko; Striebel, Maren; Urrutia-Cordero, Pablo; Vad, Csaba F.; Zadereev, Egor; Matias, Miguel (2022-05-01)
© 2021 The AuthorsThe widespread salinisation of freshwater ecosystems poses a major threat to the biodiversity, functioning, and services that they provide. Human activities promote freshwater salinisation through multipl...
SMN loss dysregulates microtubule-associated proteins in spinal muscular atrophy model
Zobaroğlu Özer, Pelin; Koyunoğlu, Dila; Son, Çağdaş Devrim; Erdem-Yurter, Hayat Erdem; BORA, GAMZE (2022-05-01)
© 2022 Elsevier Inc.Spinal muscular atrophy (SMA) is a rare neurodegenerative disease caused by the absence of survival motor neuron (SMN) protein. SMN loss results in impairments of the cytoskeleton, including microtubule...
The structural effects of Vitamin A deficiency on biological macromolecules due to ethanol consumption and withdrawal: An FTIR study with chemometrics
ELİBOL, BİRSEN; Severcan, Mete; Jakubowska-Dogru, Ewa; DURSUN, İLKNUR; Severcan, Feride (2022-04-01)
The structural effects of vitamin A-deficiency were examined on the molecular profiles of biomolecules of male rat hippocampus during prolonged ethanol intake/withdrawal using FT-IR spectroscopy coupled with chemometrics. ...
Disentangling the importance of space and host tree for the beta-diversity of beetles, fungi, and bacteria: Lessons from a large dead-wood experiment
Rieker, Daniel; Krah, Franz-S.; Gossner, Martin M.; Uhl, Britta; Ambarlı, Didem; Baber, Kristin; Buscot, François; Hofrichter, Martin; Hoppe, Björn; Kahl, Tiemo; Kellner, Harald; Moll, Julia; Purahong, Witoon; Seibold, Sebastian; Weisser, Wolfgang W.; Bässler, Claus (2022-04-01)
© 2022 Elsevier LtdForestry in Europe changed the tree species composition and reduced dead-wood amount and heterogeneity, and therefore negatively affected saproxylic diversity. Efficient conservation requires knowledge a...
TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior.
Yanpallewar, Sudhirkumar; Tomassoni-Ardori, Francesco; Palko, Mary Ellen; Hong, Zhenyi; Kiriş, Erkan; Becker, Jodi; Fulgenzi, Gianluca; Tessarollo, Lino (2022-03-17)
Recent studies have suggested that the use of cognitive enhancers as adjuncts to exposure-based therapy in individuals suffering from post-traumatic stress disorder (PTSD) may be beneficial. Brain cholinergic signaling thr...
Genetic diversity and population structure of Salix alba across river systems in Turkey and their importance in conservation management
Özdemir Değirmenci, Funda; Çiftçi, Asiye; Acar, Pelin; Kaya, Zeki (2022-03-01)
Background Salix alba is a pioneer species of river ecosystems throughout Turkey. Its genetic diversity and population structure across these ecosystems is currently unknown. Aims We investigated genetic diversity in Turki...
Broad maternal geographic origin of domestic sheep in Anatolia and the Zagros
Her, Charlotte; Rezaei, Hamid-Reza; Hughes, Sandrine; Naderi, Saeid; Duffraisse, Marilyne; Mashkour, Marjan; Naghash, Hamid-Reza; Balasescu, Adrian; Luikart, Gordon; Jordan, Steve; Ozut, Deniz; KENCE, AYKUT; Bruford, Michael W.; Tresset, Anne; Vigne, Jean-Denis; Taberlet, Pierre; Hanni, Catherine; Pompanon, Francois (2022-03-01)
We investigated the controversial origin of domestic sheep (Ovis aries) using large samples of contemporary and ancient domestic individuals and their closest wild relatives: the Asiatic mouflon (Ovis gmelini), the urial (...
Xenogenic Neural Stem Cell-Derived Extracellular Nanovesicles Modulate Human Mesenchymal Stem Cell Fate and Reconstruct Metabolomic Structure
DERKUŞ, BURAK; Isik, Melis; Eylem, Cemil Can; ERGİN, İREM; Camci, Can Berk; Bilgin, Sila; ELBÜKEN, ÇAĞLAR; ARSLAN, YAVUZ EMRE; Akkulak, Merve; Adalı, Orhan; KIRAN, FADİME; Okesola, Babatunde O.; NEMUTLU, EMİRHAN; EMREGÜL, EMEL (2022-03-01)
Extracellular nanovesicles, particularly exosomes, can deliver their diverse bioactive biomolecular content, including miRNAs, proteins, and lipids, thus providing a context for investigating the capability of exosomes to ...
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