Developing enteral feeding formulations with different protein sources, rheological characterization and microstructural analysis of these formulations

Atıl, Gökhan Uğur
People who underwent surgery or suffer from dysphagia disease cannot consume solid food materials. Liquid food formulations which are called as enteral feeding formulations are prepared for these people. The main objective of this study was to investigate the usage possibilities of different plant-based proteins in enteral nutrition products and to examine the effects of these proteins on these products such as rheology, stability and microstructure. In the first part of this study protein concentrates were extracted from lentil, chickpea, mung bean and quinoa. Extracted proteins and two commercial proteins which are pea protein concentrate and soy protein concentrate were characterized. In order to characterize these protein concentrates, proximate analysis, amino acid analysis, WHC, OBC, FTIR analysis and scanning electron microscopy analysis were carried out. In the second part of this study, these proteins were used to formulate enteral nutrition products together with those currently used in the industry. After formulation step, particle size analysis and stability analysis were conducted. Rheological and microstructural properties were also investigated by using rheometer and confocal laser scanning microscope (CLSM), respectively. All enteral products which were prepared with different protein and fat sources were compared with commercial enteral product.


Generation of aptamer against salmonella serovar enteritidis and development of aptamer-based capillary biosensor
Bayraç, Ceren; Öktem, Hüseyin Avni; Eyidoğan, Füsun İnci; Department of Biotechnology (2014)
Food poisoning became one of the most important diseases that threaten to human health. Among all the food-borne pathogens, Salmonella is the most common cause of food-borne infectious disease in the world. Among over 2500 serovars, Salmonella enterica serovar Enteritidis is a common foodborne pathogen associated with human diseases. Limited and time consuming diagnostic techniques such as culturing method or polymerase chain reaction lead to increase in the demands of new detection methods. Therefore, in t...
Effect of different flours on quality of gluten-free wafer sheet
Mert, Selen; Şahin, Serpil; Şümnü, Servet Gülüm; Department of Food Engineering (2014)
Lifelong gluten-free diet is essential for patients having celiac disease. Since wheat flour contains gluten, it is necessary to replace wheat flour with other types of gluten-free flours. Rice flour is commonly used in gluten-free baked products as an alternative to wheat flour. The main objective of this study was to develop gluten-free wafer sheet formulations by replacing rice flour partially with different gluten-free flours at different ratios. Rice-corn flour blends, rice-buckwheat flour blends and r...
Development of nanocomposite hydrogels for controlled release of proteins
Sivri, Seda; Bat, Erhan; Yılmazer, Ülkü; Department of Chemical Engineering (2016)
Owing to the fact that a vast number of biological functions are performed via proteins in living tissues, many human diseases are resulted from the malfunction or deficiency of particular proteins. Hence, there has been extensive work on industrial production of therapeutic proteins for the treatment of diseases in recent years. However, proteins could be denatured or degraded in vivo in a short time before reaching target site due to their fragile nature. Additionally, owing to the renal clearance and sho...
Development of nucleic acid based lateral flow immunochromatographic test platform for salmonella detection
Bulut, Onur; Öktem, Hüseyin Avni; Department of Biology (2014)
Foodborne diseases have been a crucial problem for the public health. Various agents transmitted by food cause these diseases. However, Salmonella accounts for most of the cases leading to most of the hospitalization and even death. Therefore, rapid detection of Salmonella is a considerable step in order to improve food safety and minimize outbreaks. Nucleic acid based biosensors are fast, simple, economic, easy-to-use and do not require trained personnel or high-cost equipments when compared to the current...
Effect of maternal high fat diet on hypothalamus vacularite of their offspring /
Teker, Hikmet Taner; Yanık, Tülin; Purutçuoğlu Gazi, Vilda; Department of Biotechnology (2014)
Obesity is a medical condition that carries increased risk for the onset of metabolic disorders and many other chronic diseases. However, etiology of obesity and how obsegenic traits are emerged remain to be elucidated. Investigations about this issue focused on one of the brain regions, hypothalamus,where energy homeostasis,food intake and appetite are regulated. Under the condition of hypothalamic inflammation and/or because of the passage of toxic substances from the circulating blood to the hypothalamus...
Citation Formats
G. U. Atıl, “Developing enteral feeding formulations with different protein sources, rheological characterization and microstructural analysis of these formulations,” M.S. - Master of Science, Middle East Technical University, 2021.