Physical, antimicrobial and antibiofilm properties of Zataria multiflora Boiss essential oil nanoemulsion

Shahabi, Nasim
Tajik, Hossein
Moradi, Mehran
Forough, Mehrdad
Ezati, Parya
It was evaluated physical, antibacterial and antibiofilm properties of Zataria multiflora Boiss essential oil (ZEO) and its nanoemulsion. Long-term stability of nanoemulsion prepared by emulsion phase inversion was satisfying based on low narrow size distribution (polydispersity index 0.2) and low droplet size (200nm) over 21 days of storage. Nanoemulsion showed lower minimum inhibitory concentration (MIC) on Listeria monocytogenes (2500 mu gmL(-1)) than Salmonella Typhimurium (5000 mu gmL(-1)). Killing kinetics study revealed that nanoemulsion was more effective in inhibiting the growth of bacteria in milk than culture media. Both bacteriostatic and bactericidal effects were observed depending on the type of bacteria, nanoemulsion concentration and the time of exposure. Nanoemulsion at 4xMIC concentration reduced 64% and 75% of one-day-old biofilm of L.monocytogenes and S.Typhimurium, respectively. In conclusion, nanoemulsion revealed antimicrobial activity, but converting the ZEO to nanoemulsion did not improve its antibacterial activity; however, antibiofilm properties were enhanced.


Enantioselective Michael addition of malononitrile to chalcone with bifunctional squaramide organocatalysts
Sargın, Nurdan; Tanyeli, Cihangir; Department of Chemistry (2015)
4H-pyran derivatives show diverse biological activity such as antimicrobial, antibacterial, antiviral and antifungal. 4H-pyran derivatives can be synthesized easily from 2-(3-oxo-1,3-diphenylpropyl)malononitrile which is the Michael addition product of malononitrile to trans-chalcone. Synthesizing chiral biologically active compounds with metal free approach (organocatalysis) is a significant topic. In this thesis, chiral 2-(3-oxo-1,3-diphenylpropyl)malononitrile was synthesized with quinine or 2-aminoDMAP ...
Nanostructured chitosan/monolaurin film: Preparation, characterization and antimicrobial activity against Listeria monocytogenes on ultrafiltered white cheese
Lotfi, Mohamad; Tajik, Hossein; Moradi, Mehran; Forough, Mehrdad; Divsalar, Elahe; Kuswandi, Bambang (2018-06-01)
Antimicrobial cellulose-chitosan (CC) films containing monolaurin (ML) (0.5 and 1%) were developed using the sol-gel method and characterized in terms of microscopic, structural, swelling, water solubility, and antimicrobial properties against Listeria monocytogenes in vitro and on ultrafiltered cheese during storage at 4 for 14 days. The results of antimicrobial activity revealed that the addition of ML significantly (p < 0.05) increased the diameter of the inhibition zone. Moreover, CC film did not show i...
Covalent immobilization of invertase on chemically activated poly(2-hydroxyethyl methacrylate) microbeads
Altinok, H.; Aksoy, S.; Tumturk, H.; Hasırcı, Nesrin (2006-10-01)
Properties of invertase immobilized on poly(2-hydroxyethyl methacrylate) microbeads activated by epichlorohydrin or cyanuric chloride were studied. After 20 repeated uses for 3 days, the activity of the immobilized enzyme was 92-93%.
Electrochemical biosensor based on three components random conjugated polymer with fullerene (C60)
KURBANOĞLU, SEVİNÇ; Cevher, Sevki Can; Toppare, Levent Kamil; Çırpan, Ali; Soylemez, Saniye (2022-10-01)
© 2022 Elsevier B.V.Herein, a conjugated polymer and fullerene bearing architecture-based electrochemical Tyrosinase (Tyr) enzyme inhibition biosensor for indomethacin (INDO) drug active compound has been developed. For this purpose, three moieties of benzoxadiazole, thienopyrroledione, and benzodithiophene containing conjugated polymer; poly[BDT-alt-(TP;BO)] was used as a transducer modifier together with fullerene for catechol detection. The specific combination of these materials is considered an effecti...
Performance evaluation of Cappadocian tuffs treated with alcohol dispersion of calcium hydroxide nano-particles
Çalışkan, Berkay Barış; Tavukçuoğlu, Ayşe; Saltık, Emine Nevin; Department of Building Science in Architecture (2022-12-08)
In this study, the effect of treatment with alcohol dispersion of calcium hydroxide Ca(OH)2 nanoparticles on controlling excessive water absorption and capillary water suction properties of Cappadocian tuffs was investigated extensively. For this purpose, two tuff types, Göreme Rock (CYT) and Cappadocian Rose (CPT), obtained from a quarry near Avanos-Nevşehir, were examined. Laboratory tests were conducted concerning their basic physical, hygric, mechanical, microstructural, and mineralogical properties bef...
Citation Formats
N. Shahabi, H. Tajik, M. Moradi, M. Forough, and P. Ezati, “Physical, antimicrobial and antibiofilm properties of Zataria multiflora Boiss essential oil nanoemulsion,” INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, pp. 1645–1652, 2017, Accessed: 00, 2021. [Online]. Available: