3D silk fibroin scaffolds for tissue engineering applications

Date

2021-06-10

Author

Kafalı, Melisa
Ercan, Batur

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Silk fibroin (SF) gained attention in tissue engineering applications owing to its unique properties including biocompatibility, high strength and ability to control its porous structure. The aim of this study was to fabricate 3D SF scaffolds having an optimum porous structure to provide sufficient mechanical properties while allowing proliferation of cells for enhanced tissue regeneration. To achieve this, effect of various fabrication parameters on SF scaffold characteristics, mainly the pore morphology and pore size, on mechanical and biological properties was investigated. Specifically, dissolution time of raw SF in salt solution, dialysis temperature, freezing rate and freezing temperature of SF solutions were optimized for detailed scaffold characterization.

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http://www.immc-mtm.com/index-eng.html
https://hdl.handle.net/11511/91258

Conference Name

20. Uluslararası Metalurji ve Malzeme Kongresi

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Department of Metallurgical and Materials Engineering, Conference / Seminar

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Citation Formats

M. Kafalı and B. Ercan, “3D silk fibroin scaffolds for tissue engineering applications,” presented at the 20. Uluslararası Metalurji ve Malzeme Kongresi, 2021, Accessed: 00, 2021. [Online]. Available: http://www.immc-mtm.com/index-eng.html.