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A novel approach for the fabrication of a flexible glucose biosensor: The combination of vertically aligned CNTs and a conjugated polymer
Date
2017-04-01
Author
GOKOGLAN, Tugba Ceren
SOYLEMEZ, Saniye
KESİK, Melis
DOGRU, Itir Bakis
TUREL, Onur
YÜKSEL, Recep
Ünalan, Hüsnü Emrah
Toppare, Levent Kamil
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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A novel flexible glucose biosensor using vertically aligned carbon nanotubes (VACNT) and a conjugated polymer (CP) was fabricated. A scaffold based on VACNT grown on aluminum foil (VACNT-Al foil) with poly (9,9-di-(2-ethylhexyl)-fluorenyl-2,7-diyl)-end capped with 2,5-diphenyl-1,2,4-oxadiazole (PFLO) was used as the immobilization matrix for the glucose biosensor. Glucose oxidase (GOx) was immobilized on a modified indium tin oxide (ITO) coated polyethylene terephthalate (PET) electrode surface. The biosensor response at a potential of -0.7 V versus Ag wire was followed by the decrease in oxygen level as a result of enzymatic reaction. The biosensor exhibited a linear range between 0.02 mM and 0.5 mM glucose and kinetic parameters (K-M(app), I-max, limit of detection (LOD) and sensitivity) were estimated as 0.193 mM, 8.170 mu A, 7.035 x 10(-3) mM and 65.816 mu A/mM cm(2), respectively. Scanning electron microscopy (SEM) was used for surface characterization. The constructed biosensor was applied to determine the glucose content in several beverages.
Subject Keywords
Conjugated Polymer
,
Glucose Oxidase
,
Enzyme Electrode
,
Amperometric Biosensor
,
Vertically Aligned Carbon Nanotubes
,
Glucose Biosensor
URI
https://hdl.handle.net/11511/42240
Journal
FOOD CHEMISTRY
DOI
https://doi.org/10.1016/j.foodchem.2016.10.023
Collections
Department of Metallurgical and Materials Engineering, Article
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T. C. GOKOGLAN et al., “A novel approach for the fabrication of a flexible glucose biosensor: The combination of vertically aligned CNTs and a conjugated polymer,”
FOOD CHEMISTRY
, pp. 299–305, 2017, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/42240.