Synthesis and applications of ion incorporated amorphous calcium-magnesium carbonate

2023-1-18
Göçtü, Yağmur
Amorphous calcium carbonate (ACC) can be synthesized using co-precipitation technique and different ions can typically be incorporated into its amorphous structure to enhance its stability. Although ACC was investigated for various applications, its antibacterial properties have not been explored. In this thesis, two different types of magnesium stabilized amorphous calcium carbonate (ACMC) nanoparticles were synthesized for antibacterial applications. In the first part selenite ions, and in the second part zinc and strontium ions were incorporated into the ACMC nanoparticles. It was shown that ion incorporated ACMC nanoparticles maintained their amorphous structure. The synthesized nanoparticles inhibited bacterial growth of several bacteria strains. 0.01, 0.005 and 0.001 M selenite incorporated ACMC nanoparticles prepared at 1 g/L concentration significantly inhibited the growth of gram-positive Staphylococcus aureus (S. aureus) and Staphylococcus epidermidis (S. epidermidis) and gram-negative Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa) strains after 24 h of interaction. The antibacterial activity was shown to enhance as the amount of incorporated selenite was increased. On the other hand, zinc and/or strontium incorporated (0.1 and 0.01 M) ACMC nanoparticles prepared at 0.01 g/L concentration exerted antibacterial activity towards S. aureus, and the extend of this antibacterial activity could also be enhanced by ion concentration, where higher amounts (0.1 M) of Zn and Sr incorporated ACMC nanoparticles were able to decrease the growth of E. coli. In summary, in this thesis study, non-toxic and biodegradable nanoparticles were fabricated by incorporating selenite, zinc and strontium into ACMC for antibacterial applications. Results showed that ion incorporated ACMC is a potential candidate to fight with bacteria.

Suggestions

Synthesis of calcium carbonate particles for biomedical applications
Oral, Çağatay Mert; Ercan, Batur; Department of Metallurgical and Materials Engineering (2020)
Calcium carbonate (CaCO3) particles have been widely used in biomedical applications owing to their biocompatibility and biodegradability. In order to effectively utilize CaCO3 particles in biomedical applications, their physical and chemical properties should be systematically controlled. However, this is a challenging task due to the presence of three different anhydrous CaCO3 polymorphs having complex crystallization behavior. In this thesis, CaCO3 particles were synthesized at distinct environments to c...
Synthesis of CuO nanostructures on zeolite-Y and investigation of their CO2 adsorption properties
Boruban, Cansu; Nalbant Esentürk, Emren (2017-10-01)
Copper(II) oxide (CuO) nanoparticles (NPs) in two different morphologies, spiky and spherical, were synthesized on zeolite-Y by a modified impregnation method, and their CO2 adsorbing capabilities were investigated under standard conditions (1 atm and 298 K). The properties and CO2 adsorption performances of the hybrid systems were characterized by transmission electron microscopy, scanning electron microscopy, energy dispersive X-ray, X-ray diffraction, X-ray photoelectron spectroscopy, atomic absorption s...
Synthesis of alpha-Fe2O3/TiO2 heterogeneous composites by the sol-gel process and their photocatalytic activity
Bouziani, Asmae; PARK, JONGEE; Öztürk, Abdullah (Elsevier BV, 2020-09-01)
alpha-Fe2O3/TiO2 heterogeneous composites were synthesized by the sol-gel process to increase the photocatalytic activity of TiO2. The structural, morphological, and optical characteristics of the composites were determined by X-ray diffraction, scanning electron microscope, and UV-vis diffuse reflectance spectroscopy. Results revealed that the incorporation of alpha-Fe2O3 to TiO2 widened the visible light absorption ability of TiO2. It was realized that the calcination temperature plays a crucial role in m...
Fabrication and characterization of porous hydroxyapatite and biphasic calcium phosphate ceramic as bone substitutes
Koc, N; Timucin, M; Korkusuz, Feza (2004-01-01)
In the present study, the calcium phosphate powders (HAP, HAP-TCP) were produced by a precipitation technique involving the use of aqueous solutions of calcium nitrate and diammonium hydrogen phosphate. Preforms of calcium phosphate ceramics were produced by using a modified slip casting technique. Porosity in the cast and in the sintered ceramic was obtained through custom made PMMA beads similar to200-300 mum size. The green ceramic samples were prepared by suspending the apatite powder and PMMA beads in ...
Preparation and characterization of ni-nitrilotriacetic acid bearing Poly(Methacrylic acid) coated superparamagnetic magnetite nanoparticles
TURAL, Bilsen; KAYA, Murat; Özkan, Necati; Volkan, Mürvet (2008-02-01)
Stable superparamagnetic magnetite (Fe3O4) nanoparticles were synthesized via co-precipitation in the presence of poly(methacrylic acid) (PMAA) in aqueous solution. The polymer coated Fe3O4 nanoparticles were characterized using transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction, thermal analysis, and vibrating sample magnetometry (VSM) techniques. These measurements reveal the presence of magnetite nanoparticles with a size of approximately 8 nm inside...
Citation Formats
Y. Göçtü, “Synthesis and applications of ion incorporated amorphous calcium-magnesium carbonate,” M.S. - Master of Science, Middle East Technical University, 2023.