Optimization of hypericin extraction from hypericum perforatum L. tissues and evaluation of its applicability in dye-sensitized solar cells /

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2014
Aktuna, Özge
Medicinal plants which have been widely used in folk medicine are known to contain important biologically active compounds. Hypericum perforatum is one of the medicinal plants that grows in Europe, Western Asia and Northern Africa and is distinguished by its golden yellow flowers. The common name of the plant is St. John’s wort. As a practical folk-remedy, it has been used widely to heal wounds, remedy kidney troubles, and alleviate nervous disorders. Nowadays, many application areas of hypericin are discovered such as antimicrobial, antiviral, antidepressive agent. Moreover, due to its photodynamic activity, the applications of hypericin in photodynamic therapy of cancer and in designing solar panels as dye-sensitized solar cell have been researched. In order to extract hypericin from H.perforatum, ultrasonication and sonication methods were applied. Exposure times to ultrasonication and sonication, temperature, incubation time were the variables in the experiment. As a result, 20 minutes time to exposure to ultrasonication method gave the best results in analyses such as TLC, paper chromatography, spectrophotometry and LC-MS. Therefore, 20 minutes time to exposure to ultrasonication was determined as an optimum condition for extraction of hypericin. The extracted hypericin was successfully used as an organic dye in dye- sensitized solar cells.

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Citation Formats
Ö. Aktuna, “Optimization of hypericin extraction from hypericum perforatum L. tissues and evaluation of its applicability in dye-sensitized solar cells /,” M.S. - Master of Science, Middle East Technical University, 2014.