Antioxidant properties of Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. and Heracleum persicum Desf. from Apiaceae family used as food in Eastern Anatolia and their inhibitory effects on glutathione-S-transferase

Date

2007-01-01

Author

Çoruh, Nursen
Ozgokce, F.

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

166
views

0
downloads

Therapeutic effects of several medicinal plants and vegetables, which are commonly used as food and in folk medicine against many disease, are well known. Antioxidant capacities of Heracleum persicum Desf., Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. species from Apiaceae family were evaluated by determining their effects on DPPH radical scavenging, and lipid peroxidation inhibition, as well as their total phenolic contents. Potential natural glutathione-S-transferase inhibitors have gained great importance in the last decade especially because of the role of glutathione-S-transferases in developing resistance to chemotherapy. Selected plants were therefore further investigated for their influence on the activity of glutathione-S-transferase enzyme.

Subject Keywords

Antioxidant, DPPH, Phenolic content, Lipid peroxidation, Glutathione-S-transferase, GST, Apiaceae

URI

https://hdl.handle.net/11511/49294

Journal

FOOD CHEMISTRY

DOI

https://doi.org/10.1016/j.foodchem.2005.12.006

Collections

Department of Chemistry, Article

Suggestions

OpenMETU
Core

Comparative effects of emodin on biological activities of MCF-7 and MDA-231 cell lines Sakallı, Elif; İşcan, Mesude; Department of Biochemistry (2010) Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a phytoestrogenic component of Rheum plant extracts which has been used for medical treatment since ancient times. It has been shown to have anti-inflammatory and anti-cancer effects. In our research, we aimed to study the biological effects of emodin on MCF-7 and MDA-231 cell lines. Cytotoxicity assays showed that emodin treatment for 48hours caused a concentration dependent decrease in viable cell numbers of both cell lines. As determined by cell counting...
Anticarcinogenic effects of the ethanolic extract from salix aegyptiaca l. in colon cancer, involvement of akt pathway Enayat, Shabnam; Banerjee, Sreeparna; Department of Biology (2013) Salix aegyptiaca has been used for centuries as a medicinal plant for various health disorders. Our previous study demonstrated high contents of phenolics and antioxidants in its bark many of those are famed for their anti-inflammatory properties. Since inflammation frequently accompanies the progress of colorectal cancer, in the current study we showed that the ethanolic extract of bark (EEB) from S.aegyptiaca exerted strong anti-proliferative effects on several cancer cells but not on non-cancerous CCD-18...
Antioxidant and cytotoxic properties of Salvia fruticosa M. and its effects on gene expressions of some CYP450 and antioxidant enzymes in HT-29 cell line Altay, Ahmet; Bozoğlu, Faruk; Tokuşoğlu, Özlem; Department of Biochemistry (2015) Salvia genus is a widely cultivated as a perennial herb and used in medicine for various purposes due to its antimicrobial, antioxidant, anticarcinogen and anti-inflammatory properties. In this study, the phenolic composition of water extract of Salvia fruticosa and possible effects of those constituents in cancer related drug metabolizing enzymes are investigated. S. fruticosa extract displayed high Radical Scavenging Activity against DPPH and ABTS radicals and also showed high Fe2+ Chelating Activity . To...
Antioxidant and cytotoxic properties of Salvia Absconditiflora and effects on CYP1A1, CYP1B1 gene expressions in breast cancer cell lines Yılmaz, Selis; İşcan, Mesude; Güray, Tülin; Department of Biochemistry (2013) Salvia genus is a widely cultivated genus and used in medicine for various purposes as having antimicrobial, antioxidant, anticarcinogen and anti-inflammatory features. In this study the aim was to investigate phenolic composition of Salvia absconditiflora and understand the possible effects of those constituents in cancer related drug metabolizing enzymes. Salvia absconditiflora showed 80,43 % Radical Scavenging Activity against DPPH radical. Total flavonoid content was found as one third of total phenolic...
Effect of emodin on doxorubicin-induced cytotoxicity and apoptosis on MCF-7 and MCF-10a cells Kaya, Bade; Güray, Tülin; Uyar, Pembegül; Department of Biology (2014) Emodin (3-Methyl-1,6,8-trihydroxyanthraquinone), is a phytoestrogenic component of Rheum and Polygonum plant extracts which has been used to treat several diseases since ancient times. It has been shown to have anti-microbial, anti-oxidant and anti-cancer effects in nature. The anti-tumor drug doxorubicin, a widely used chemotherapeutic agent, is used for the treatment of many cancer types including lung, gastric, ovarian and breast cancer. In this study, the effects of pre-, co- and alone treatment of doxo...

Citation Formats

N. Çoruh and F. Ozgokce, “Antioxidant properties of Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. and Heracleum persicum Desf. from Apiaceae family used as food in Eastern Anatolia and their inhibitory effects on glutathione-S-transferase,” FOOD CHEMISTRY, pp. 1237–1242, 2007, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/49294.