Ali Deniz Dalgıç

Department of Engineering Sciences
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Lanthanum doped dicalcium phosphate bone cements for potential use as filler for bone defects
Motameni, Ali; Alshemary, Ammar Z.; Dalgıç, Ali Deniz; Keskin, Dilek; Evis, Zafer (2021-03-01)
The bone defects arising as a result of trauma should be filled to provide a framework to support and encourage the growth of new and living bone tissues. Among the many synthetic bone graft substitutes, self-hardening cal...
Structural and Biological Analysis of Mesoporous Lanthanum Doped beta TCP For Potential Use as Bone Graft Material
Motameni, Ali; Dalgıç, Ali Deniz; ALSHEMARY, AMMAR ZEIDAN GHAILAN; Keskin, Dilek; Evis, Zafer (Elsevier BV, 2020-06-01)
In this study, mesoporous particles of beta-tricalcium phosphate (beta TCP, beta Ca-3(PO4)(2)) and lanthanum (La) doped beta TCP were synthesized using wet precipitation method attached with microwave refluxing system. The...
A comparative study of monoaxial and coaxial PCL/gelatin/Poloxamer 188 scaffolds for bone tissue engineering
Alissa Alam, Hani; Dalgıç, Ali Deniz; Tezcaner, Ayşen; Özen, Can; Keskin, Dilek (2020-04-01)
Structure of fibrous scaffolds varies depending on the electrospinning method and parameters which will define cell fate. In this study, monoaxial and coaxial electrospun PCL/gelatin/P-188 scaffolds were characterized in t...
Nanocrystalline Zn2+ and SO42- binary doped fluorohydroxyapatite: A novel biomaterial with enhanced osteoconductive and osteoinconductive properties
ALSHEMARY, AMMAR ZEIDAN GHAILAN; Pazarçeviren, Ahmet Engin; Dalgıç, Ali Deniz; Tezcaner, Ayşen; Keskin, Dilek; Evis, Zafer (2019-11-01)
In this study, we have successfully doped hydroxyapatite (HA) with zinc (Zn2+), sulphate (SO42-) and fluoride (F-) ions to develop a new composition of bioceramic, Ca10-xZnx(PO4)(6-y)(SO4)(y)(OH)(2-z-y)F-z(SO4)(y), (x = 0,...
Diatom shell incorporated PHBV/PCL-pullulan co-electrospun scaffold for bone tissue engineering
Dalgıç, Ali Deniz; Atila, Deniz; Karataş, Ayten; Tezcaner, Ayşen; Keskin, Dilek (Elsevier BV, 2019-07-01)
Tissue engineering can benefit from wide variety of materials produced by microorganisms. Natural origin materials often possess good biocompatibility, biodegradability with sustainable production by microorganisms. A phyt...
A new therapeutic combination for osteosarcoma: Gemcitabine and Clofazimine co-loaded liposomal formulation
Caliskan, Yagmur; Dalgıç, Ali Deniz; Gerekci, Selin; Gulec, Ezgi A.; Tezcaner, Ayşen; Özen, Can; Keskin, Dilek (2019-02-25)
Osteosarcoma is the most common cancer in bone. Drug resistance is a challenge of current treatments that needs to be improved with novel treatment strategies. In this research, a new dual drug delivery system was develope...
Diatom silika kabuk katkılı PHBV/PCL-pullulan taşıyıcıların kemik doku mühendisliğine uygunluğunun araştırılması
Dalgıç, Ali Deniz; Atila, Deniz Hazal; Koman, Ezgi; Karataş, Ayten; Tezcaner, Ayşen; Keskin, Dilek (2018-12-15)
Graphene Oxide Incorporated Silicate Doped Nano-hydroxyapatite Novel Composite for Bone Tissue Engineering
Dalgıç, Ali Deniz; Alshemary, Ammar Zeıdan Ghaılan; Tezcaner, Ayşen; Keskin, Dilek; Evis, Zafer (2018-06-05)
Hydroxyapatite, as the natural inorganic phase of the bone tissue has been widely used as the main structure of bone tissue scaffolds. In studies, ion substitution into hydroxyapatite structure enhanced the osteogenic prop...
Silicate-doped nano-hydroxyapatite/graphene oxide composite reinforced fibrous scaffolds for bone tissue engineering
Dalgıç, Ali Deniz; Alshemary, Ammar Z.; Tezcaner, Ayşen; Keskin, Dilek; Evis, Zafer (SAGE Publications, 2018-3-15)
In this study, novel graphene oxide-incorporated silicate-doped nano-hydroxyapatite composites were prepared and their potential use for bone tissue engineering was investigated by developing an electrospun poly(epsilon-ca...
Maltodextrin modified liposomes for drug delivery through the blood-brain barrier
GURTURK, Zeynep; Tezcaner, Ayşen; Dalgıç, Ali Deniz; KORKMAZ, Seval; Keskin, Dilek (2017-06-01)
Central nervous system acting drugs, when administered intravenously, cannot show their effect in the brain due to the difficulty in crossing the blood-brain barrier (BBB). Levodopa is one of those drugs that are used to t...
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