Hepşen Hazal Hüsnügil

E-mail

hazalh@metu.edu.tr

Department

Department of Biology

ORCID

0000-0002-5910-6243

Scopus Author ID

57193009112

Web of Science Researcher ID

ABA-1308-2020

Lysosomal alkalinization in nutrient restricted cancer cells activates cytoskeletal rearrangement to enhance partial epithelial to mesenchymal transition Hüsnügil, Hepşen Hazal; Güleç Taşkıran, Aliye Ezgi; Güderer, İsmail; Nehri, Leman Nur; Oral, Göksu; Menemenli, Nazlı Şevval; Özcan, Özün; Noghreh, Ariana; AKYOL, AYTEKİN; Banerjee, Sreeparna (2024-03-01) Introduction: Nutrient restriction in cancer cells can activate a number of stress response pathways for cell survival. We aimed to determine mechanistically how nutrient depletion in colorectal cancer (CRC) cells leads to...
A partial epithelial-mesenchymal transition signature for highly aggressive colorectal cancer cells that survive under nutrient restriction Pastorino, Gil A; Sheraj, Ilır; Huebner, Kerstin; Ferrero, Giulio; Kunze, Philipp; Hartmann, Arndt; Hampel, Chuanpit; Hüsnügil, Hepşen Hazal; Maiuthed, Arnatchai; Gebhart, Florian; Schlattmann, Fynn; Gulec Taskiran, Aliye Ezgi; Oral, Goksu; Palmisano, Ralph; Pardini, Barbara; Naccarati, Alessio; Erlenbach-Wuensch, Katharina; Banerjee, Sreeparna; Schneider-Stock, Regine (2024-03-01) Partial epithelial-mesenchymal transition (p-EMT) has recently been identified as a hybrid state consisting of cells with both epithelial and mesenchymal characteristics and is associated with the migration, metastasis, an...
Investigation of the effects of nutrient restriction on endolysosomal signaling in colorectal cancer (CRC) cells. Gulec, Aliye E.; Hüsnügil, Hepşen Hazal; Oral, Goksu; Sheraj, Ilir; Banerjee, Sreeparna (2021-07-01)
INVESTIGATION OF THE EFFECTS OF NUTRIENT RESTRICTION ON LYSOSOMAL TRAFFICKING IN COLORECTAL CANCER CELLS Hüsnügil, Hepşen Hazal; Oral, Göksu; Erson Bensan, Ayşe Elif; Banerjee, Sreeparna (2021-04-10)
ANALYSIS OF A POTENTIAL MICRORNA NETWORK THAT CO-REGULATES AUTOPHAGY AND EPITHELIAL TO MESENCHYMAL TRANSITION UNDER NUTRIENT RESTRICTION Hüsnügil, Hepşen Hazal; Sheraj, Ilir; Erson Bensan, Ayşe Elif; Banerjee, Sreeparna (2020-10-23)
Nutrient Restriction Induced Cell Death in Caco-2 Colon cancer Cells’Nutrient Restriction Induced Cell Death in Caco-2 Colon cancer Cells’ Hüsnügil, Hepşen Hazal; Banerjee, Sreeparna (2019-09-29)
Peptidomic characterization and bioactivity of Protoiurus kraepelini (Scorpiones: Iuridae) venom Doğan, Tuğba; BİBER, Aysenur; GEREKCİ, Selin; Hüsnügil, Hepşen Hazal; Özen, Can (2018-01-01) Protoiurus kraepelini is a scorpion species found in parts of Turkey and Greece. In this study, the peptide profile of its venom was determined for the first time. The electrophoretic profile of the crude venom showed a pr...
Anti-Cancer Effects of Clofazimine As a Single Agent and in Combination with Cisplatin in Multiple Myeloma Durusu, Ipek; Hüsnügil, Hepşen Hazal; Atas, Heval; Biber, Aysenur; Gerekci, Selin; Gulec, Aliye Ezgi; Özen, Can (2016-12-02) Multiple Myeloma (MM) is a malignant neoplasm of bone marrow plasma B cells with high morbidity. Clofazimine (CLF) is an FDA-approved leprostatic, anti-tuberculosis, and anti-inflammatory drug that was previously shown to ...
Cytotoxic Effect of Kv1.3 Blocker Clofazimine on HCT-116 Colon Cancer Cell Line Hüsnügil, Hepşen Hazal; İğci, Naşit; Banerjee, Sreeparna; Özen, Can (2015-05-18)
Discovery of Novel Potassium Ion Channel Blocing Peptides from Scorpion Venom Hüsnügil, Hepşen Hazal; Ağyüz, Umut; Biber, Ayşenur; Özen, Can (2014-09-14)

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