Hepşen Hazal Hüsnügil

E-mail

hazalh@metu.edu.tr

Department

Department of Biology

ORCID

0000-0002-5910-6243

Scopus Author ID

57193009112

Web of Science Researcher ID

ABA-1308-2020

Lysosome-mitochondria crosstalk in nutrient-restricted cells remodel cell signalling for survival Hüsnügil, Hepşen Hazal; Nehri, Leman Nur; Güleç Taşkıran, Aliye Ezgi; Abdullazade, Seljan Khatun; Özcan, Özün; Çatalak Yılmaz, Hazal Beril; Banerjee, Sreeparna (2025-07-07)
Survival tactics of nutrient deprived cancer cells Banerjee, Banerjee; Taskiran, A. E. Gulec; Hüsnügil, Hepşen Hazal; Menemenli, N. S.; Oral, G.; Erkan, L. N. (2025-07-01)
Spontaneous Differentiation and Autophagy Modulation in Caco-2 and T84 Colorectal Cancer Cells Güleç Taşkıran, Aliye Ezgi; Hüsnügil, Hepşen Hazal; Sheraj, Ilir; Banerjee, Sreeparna (2025-05-08)
Nutrient Restriction and Lysosomal Alkalinization Remodel Apoptosis Signaling Through Lipid Oxidation, Leading to Metastatic Transformation Hüsnügil, Hepşen Hazal; Nehri, Leman Nur; Banerjee, Sreeparna (2024-09-14)
Post-Transcriptional Regulation of Rab7a in Lysosomal Positioning and Drug Resistance in Nutrient-Limited Cancer Cells Güleç Taşkıran, Aliye Ezgi; Hüsnügil, Hepşen Hazal; Soltani, Zahra E.; Oral, Göksu; Menemenli, Nazlı S.; Hampel, Chuanpit; Huebner, Kerstin; Erlenbach-Wuensch, Katharina; Sheraj, Ilır; Schneider-Stock, Regine; Akyol, Aytekin; Liv, Nalan; Banerjee, Sreeparna (2024-09-01) Limited nutrient availability in the tumor microenvironment can cause the rewiring of signaling and metabolic networks to confer cancer cells with survival advantages. We show here that the limitation of glucose, glutamine...
A partial epithelial-mesenchymal transition signature for highly aggressive colorectal cancer cells that survive under nutrient restriction Pastorino, Gil A; Sheraj, Ilır; Huebner, Kerstin; Ferrero, Giulio; Kunze, Philipp; Hartmann, Arndt; Hampel, Chuanpit; Hüsnügil, Hepşen Hazal; Maiuthed, Arnatchai; Gebhart, Florian; Schlattmann, Fynn; Gulec Taskiran, Aliye Ezgi; Oral, Goksu; Palmisano, Ralph; Pardini, Barbara; Naccarati, Alessio; Erlenbach-Wuensch, Katharina; Banerjee, Sreeparna; Schneider-Stock, Regine (2024-03-01) Partial epithelial-mesenchymal transition (p-EMT) has recently been identified as a hybrid state consisting of cells with both epithelial and mesenchymal characteristics and is associated with the migration, metastasis, an...
Lysosomal alkalinization in nutrient restricted cancer cells activates cytoskeletal rearrangement to enhance partial epithelial to mesenchymal transition Hüsnügil, Hepşen Hazal; Güleç Taşkıran, Aliye Ezgi; Güderer, İsmail; Nehri, Leman Nur; Oral, Göksu; Menemenli, Nazlı Şevval; Özcan, Özün; Noghreh, Ariana; AKYOL, AYTEKİN; Banerjee, Sreeparna (2024-03-01) Introduction: Nutrient restriction in cancer cells can activate a number of stress response pathways for cell survival. We aimed to determine mechanistically how nutrient depletion in colorectal cancer (CRC) cells leads to...
Nutrient restriction in cancer cells activate multiple signaling pathways for survival. Güleç Taşkıran, Aliye Ezgi; Hüsnügil, Hepşen Hazal; Oral, Göksu; Menemenli, Nazlı Şevval; Huebner, Kerstin; Hampel, Chuanpit; Özcan, Özün; Akyol, Aytekin; Schneider-Stock, Regine; Liv, Nalan; Banerjee, Sreeparna (2024-02-06)
The Chorioallantoic Membrane (CAM) Assay for the Analysis of Starvation-Induced Autophagy Menemenli, Nazlı Şevval; Özcan, Özün; Hüsnügil, Hepşen Hazal; GÜLEÇ TAŞKIRAN, ALİYE EZGİ; Oral, Göksu; AKYOL, AYTEKİN; Banerjee, Sreeparna (Humana Press, 2024-01-01)
Effect of Periodate-Induced Cross-linking on Dual Anticancer Drug Release from Poly(2-isopropyl-2-oxazoline)/Tannic Acid-Based Layer-by-Layer Microparticles Ugur, Esma; Tidim, Gökçe; Gündoğdu, Dilara; Alemdar, Cemre; Oral, Goksu; Hüsnügil, Hepşen Hazal; Banerjee, Sreeparna; Erel Göktepe, İrem (2024-01-01) This study reports, first, on the preparation and cross-linking of multilayers composed of poly(2-isopropyl-2-oxazoline-co-ethyleneimine) (PiPOX-PEI) and tannic acid (TA). PiPOX was synthesized by cationic ring-opening pol...

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