Tissue engineering of oral mucosa: a shared concept with skin

Date

2015-03-01

Author

Kinikoglu, Beste
Damour, Odile
Hasırcı, Vasıf Nejat

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Tissue-engineered oral mucosa, in the form of epithelial cell sheets or full-thickness oral mucosa equivalents, is a potential solution for many patients with congenital defects or with tissue loss due to diseases or tumor excision following a craniofacial cancer diagnosis. In the laboratory, it further serves as an in vitro model, alternative to in vivo testing of oral care products, and provides insight into the behavior of the oral mucosal cells in healthy and pathological tissues. This review covers the old and new generation scaffold types and materials used in oral mucosa engineering; discusses similarities and differences between oral mucosa and skin, the methods developed to reconstruct oral mucosal defects; and ends with future perspectives on oral mucosa engineering.

Subject Keywords

Tissue engineering, Biomaterials, Polymeric scaffold, Oral mucosa, Skin

URI

https://hdl.handle.net/11511/30293

Journal

JOURNAL OF ARTIFICIAL ORGANS

DOI

https://doi.org/10.1007/s10047-014-0798-5

Collections

Graduate School of Natural and Applied Sciences, Article

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Citation Formats

B. Kinikoglu, O. Damour, and V. N. Hasırcı, “Tissue engineering of oral mucosa: a shared concept with skin,” JOURNAL OF ARTIFICIAL ORGANS, pp. 8–19, 2015, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/30293.