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Nanoparticle-based drug delivery in cancer: the role of cell membrane structures
Date
2016-11-01
Author
Yalcin, Serap
Ozluer, Ozlem
Gündüz, Ufuk
Metadata
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Development of novel drug-delivery systems aims to specifically deliver anticancer drugs to tumor tissues and improve the efficiency of chemotherapy, while minimizing side effects of drugs on healthy tissues and organs. However, drug-delivery systems are confronted by membrane barriers and multiple drug resistance in cancer cells. In recent years, the obtained results indicate an important role of lipids, proteins and carbohydrates in apoptosis, drug transport and the process of cellular uptake of nanoparticles via endocytosis. This article discusses the hypothesis of the relationship between cell membrane structure and nanoparticles in cancer cells.
Subject Keywords
Cancer
,
Cell membrane structures
,
Nanoparticles
URI
https://hdl.handle.net/11511/30557
Journal
THERAPEUTIC DELIVERY
DOI
https://doi.org/10.4155/tde-2016-0056
Collections
Graduate School of Natural and Applied Sciences, Article
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S. Yalcin, O. Ozluer, and U. Gündüz, “Nanoparticle-based drug delivery in cancer: the role of cell membrane structures,”
THERAPEUTIC DELIVERY
, pp. 773–781, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/30557.