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In vivo half life of nanoencapsulated L-asparaginase
Date
2002-12-01
Author
Baran, ET
Ozer, N
Hasırcı, Vasıf Nejat
Metadata
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In the present study, antileukemic enzyme L-asparaginase (ASNase) was encapsulated into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanocapsules in order to decrease the immunogenicity and toxicity of the enzyme and to increase its in vivo half life in mice.
Subject Keywords
In-vivo
,
Antibiotic release
,
Protein carriers;
,
Nanoparticles
,
Serum
,
Pharmacokinetics
,
Biodistribution
,
Erythrocytes
URI
https://hdl.handle.net/11511/30836
Journal
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
DOI
https://doi.org/10.1023/a:1021125617828
Collections
Graduate School of Natural and Applied Sciences, Article
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E. Baran, N. Ozer, and V. N. Hasırcı, “In vivo half life of nanoencapsulated L-asparaginase,”
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
, pp. 1113–1121, 2002, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/30836.