Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Open Access Guideline
Open Access Guideline
Postgraduate Thesis Guideline
Postgraduate Thesis Guideline
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
ALCAM (Activated Leukocyte Cell Adhesion Molecule)
Download
index.pdf
Date
2018-01-01
Author
Yavuz, Esra
ÖYKEN, MERVE
Erson Bensan, Ayşe Elif
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
206
views
95
downloads
Cite This
ALCAM (Activated Leukocyte Cell Adhesion Molecule), also known as CD166 (cluster of differentiation 166), is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain.
Subject Keywords
ALCAM
,
CD166
,
Cell adhesion
URI
https://hdl.handle.net/11511/35005
Journal
Atlas of Genetics and Cytogenetics in Oncology and Haematology
DOI
https://doi.org/10.4267/2042/68876
Collections
Department of Biology, Article
Suggestions
OpenMETU
Core
ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2
Huebner, Kerstin; et. al. (2022-08-01)
In cancer, the activating transcription factor 2 (ATF2) has pleiotropic functions in cellular responses to growth stimuli, damage, or inflammation. Due to only limited studies, the significance of ATF2 in colorectal cancer (CRC) is not well understood. We report that low ATF2 levels correlated with worse prognosis and tumor aggressiveness in CRC patients. NanoString gene expression and ChIP analysis confirmed trophoblast cell surface antigen 2 (TROP2) as a novel inhibitory ATF2 target gene. This inverse cor...
Investigation of the inflammatory pathways in spontaneously differentiating Caco-2 cells
Astarcı, Erhan; Banerjee, Sreeparna; Çoruh, Nursen; Department of Biochemistry (2011)
Intestinal epithelial differentiation entails the formation of highly specialized cells with specific absorptive, secretory, digestive and immune functions. Cell-cell and cell-microenvironment interactions appear to be crucial in determining the outcome of the differentiation process. Using the Caco-2 cell line that can undergo spontaneous differentiation when grown past confluency, we observed a loss of VCAM1 (vascular cell adhesion molecule-1) expression while ICAM1 (intercellular cell adhesion molecule-1...
EGFR (Epidermal Growth Factor Receptor)
Hatil, Ayca Circir; Çiçek, Esra; Öyken, Merve; Erson Bensan, Ayşe Elif (2020-01-01)
© 2020 Atlas of Genetics and Cytogenetics in Oncology and Haematology.ERBB family member epidermal receptor tyrosine kinase (EGFR) is composed of 28 exons and 27 introns. EGFR codes for 11 transcripts and 8 of them are protein coding. EGFR is a transmembrane glycoprotein that can be activated by several different ligands such as epidermal growth factor (EGF), transforming growth factor-alpha (TGFA), heparin-binding EGF-like growth factor (HBEGF), betacellulin (BTC), amphiregulin (AREG), epiregulin (EREG), a...
Loss of the Nuclear Envelope Protein LAP1B Disrupts the Myogenic Differentiation of Patient-Derived Fibroblasts
Kayman Kürekçi, Gülsüm; Acar, Aybar Can; Dinçer, Pervin R. (2022-11-01)
Lamina-associated polypeptide 1 (LAP1) is a ubiquitously expressed inner nuclear membrane protein encoded by TOR1AIP1, and presents as two isoforms in humans, LAP1B and LAP1C. While loss of both isoforms results in a multisystemic progeroid-like syndrome, specific loss of LAP1B causes muscular dystrophy and cardiomyopathy, suggesting that LAP1B has a critical role in striated muscle. To gain more insight into the molecular pathophysiology underlying muscular dystrophy caused by LAP1B, we established a patie...
Design of a sequence based miRNA clustering method; analysis of fungal miRNAs and host organism target genes
Narcı, Kübra; Akkaya, Mahinur S.; Oğul, Hasan; Department of Bioinformatics (2014)
MicroRNAs are small non-coding RNA molecules which contain 21-25 nucleotides, and function in post transcriptional regulation by inhibiting the translation of mRNA targets. miRNAs typically affect gene regulation by forming composite feed forward circuits (cFFCs) which also comprise a transcription factor (TF) and a target gene. By analyzing these cFFCs, the contribution of miRNAs in altering TF networks can be revealed. These contributions could either be the de-escalation of the target gene repertoire or ...
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
E. Yavuz, M. ÖYKEN, and A. E. Erson Bensan, “ALCAM (Activated Leukocyte Cell Adhesion Molecule),”
Atlas of Genetics and Cytogenetics in Oncology and Haematology
, pp. 87–92, 2018, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/35005.