Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Open Access Guideline
Open Access Guideline
Postgraduate Thesis Guideline
Postgraduate Thesis Guideline
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
ARID3B expression in primary breast cancers and breast cancer-derived cell lines
Date
2014-08-01
Author
ERDOGAN, Ayse Selcen Oguz
OZDEMIRLER, Nihan
ÖYKEN, MERVE
ALPER, Murat
Erson Bensan, Ayşe Elif
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
165
views
0
downloads
Cite This
ARID3B (AT-rich interaction domain 3) is a member of the family of ARID proteins, which constitutes evolutionarily conserved transcription factors implicated in normal development, differentiation, cell cycle regulation and chromatin remodeling. In addition, ARID3B has been linked to cellular immortalization, epithelial-mesenchymal transition (EMT) and tumorigenesis. Given the emerging role of ARID3B in tumor development, we examined its expression in primary patient-derived breast cancer samples and breast cancer-derived cell lines.
Subject Keywords
ARID3B expression
,
Breast cancer
,
Estrogen receptor
,
ERBB2
URI
https://hdl.handle.net/11511/35720
Journal
CELLULAR ONCOLOGY
DOI
https://doi.org/10.1007/s13402-014-0185-5
Collections
Department of Biology, Article
Suggestions
OpenMETU
Core
ARID3B expression in primary breast cancer samples
Oğuz Erdoğan, Ayşe Selcen; Erson Bensan, Ayşe Elif; Department of Biology (2014)
ARID3B (AT-rich interaction domain 3) is a member of the family of ARID proteins, which constitutes evolutionarily conserved transcription factors implicated in normal development, differentiation, cell cycle regulation and chromatin remodeling. In addition, ARID3B has been linked to cellular immortalization, epithelial-mesenchymal transition (EMT) and tumorigenesis. Given the emerging roles of ARID3B in tumor development, we examined its expression in primary patient-derived breast cancer samples to furthe...
APOBEC3B expression in drug resistant MCF-7 breast cancer cell lines
Onguru, Onder; Yalcin, Serap; Rosemblit, Cinthia; Zhang, Paul J.; Kilic, Selim; Gündüz, Ufuk (2016-04-01)
APOBEC3B belongs to a protein family of cytidine deaminases that can insert mutations in DNA and RNA as a result of their ability to deaminate cytidine to uridine. It has been shown that APOBEC3B-catalysed deamination provides a chronic source of DNA damage in breast cancers. We investigated APOBEC3B expression in four drug resistant breast cancer cell lines (Doxorubicin, Etoposide, Paclitaxel and Docetaxel resistant MCF-7 cell lines) using a novel RNA in situ hybridization technology (RNAscope) and compare...
Polyinosinic: polycytidylic acid loading onto different generations of PAMAM dendrimer-coated magnetic nanoparticles
Khodadust, Rouhollah; Mutlu, Pelin; Yalcin, Serap; Unsoy, Gozde; Gündüz, Ufuk (2013-08-01)
Poly (I:C), which is a synthetic double-stranded RNA, have significant toxicity on tumor cells. The immobilization of Poly (I:C) onto nanoparticles is important for the fabrication of targeted delivery systems. In this study, different generations of newly synthesized PAMAM dendron-coated magnetic nanoparticles (DcMNP) which can be targeted to the tumor site under magnetic field were efficiently loaded for the first time with Poly (I:C). Different generations of DcMNPs (G(2), G(3), G(4), G(5), G(6), and G(7...
Arid4b physically interacts with Tfap2c in mouse embryonic stem cells
Keskin, Ezgi Gul; Huang, Jialiang; Terzi Çizmecioğlu, Nihal (2021-01-01)
Precise regulation of gene expression is required for embryonic stem cell (ESC) differentiation. Transcription factor (TF) networks coordinate the balance of pluripotency and differentiation in response to extracellular and intracellular signals. Chromatin factors work alongside TFs to achieve timely regulation of gene expression for differentiation process. Our previous studies showed that a member of the Sin3a corepressor complex, Arid4b, is critical for proper mouse ESC differentiation into mesoderm and ...
MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system
Erson Bensan, Ayşe Elif (2008-10-01)
Since the discovery of microRNAs (miRNAs) in Caenorhabditis elegans, mounting evidence illustrates the important regulatory roles for miRNAs in various developmental, differentiation, cell proliferation, and apoptosis pathways of diverse organisms. We are just beginning to elucidate novel aspects of RNA mediated gene regulation and to understand how heavily various molecular pathways rely on miRNAs for their normal function. miRNAs are small non-protein-coding transcripts that regulate gene expression post-...
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
A. S. O. ERDOGAN, N. OZDEMIRLER, M. ÖYKEN, M. ALPER, and A. E. Erson Bensan, “ARID3B expression in primary breast cancers and breast cancer-derived cell lines,”
CELLULAR ONCOLOGY
, pp. 289–296, 2014, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/35720.