Association analysis of Glutathione S-transferase omega-1 and omega-2 genetic polymorphisms and ischemic stroke risk in a Turkish population

Date

2019-01-01

Author

Bilgin, Esra
Can Demirdöğen, Birsen
Ozcelik, Aysun Turkanoglu
Demirkaya, Seref
Adalı, Orhan

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Objectives: Oxidative stress is a known risk factor for the pathogenesis of atherosclerosis, the main cause of ischemic stroke. Glutathione S-transferase (GST) omega-1 and omega-2, members of phase II enzymes, play a role in the antioxidant system. The single nucleotide polymorphisms (SNPs), C419A and A424G in GST omega genes can cause a decrease in enzyme activity. The aim of this study was to investigate the possible association between these polymorphisms and ischemic stroke risk in a Turkish population.

Subject Keywords

Neurology, Clinical Neurology, General Medicine

URI

https://hdl.handle.net/11511/36107

Journal

NEUROLOGICAL RESEARCH

DOI

https://doi.org/10.1080/01616412.2018.1544385

Collections

Department of Biology, Article

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Citation Formats

E. Bilgin, B. Can Demirdöğen, A. T. Ozcelik, S. Demirkaya, and O. Adalı, “Association analysis of Glutathione S-transferase omega-1 and omega-2 genetic polymorphisms and ischemic stroke risk in a Turkish population,” NEUROLOGICAL RESEARCH, pp. 118–124, 2019, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/36107.