PLE and HLE catalyzed reverse enantiomeric separation of (±)-methyl-2- methoxy-1-methyl-2,5-cyclohexadiene-1-carboxylate derivatives

1999-03-26
Tanyeli, Cihangir
Sezen, Bengu
Demir, Ayhan Sıtkı
ALVES, Rosemeire Brondi
ARSENİYADİS, Simeon
We describe the diversities of hydrolase-type enzymes PLE and HLE on the hydrolysis of (+/-)-methyl-2-methoxy-1 -methyl-2,5-cyclohexadiene-1-carboxylate and (+/-)-methyl-2-methoxy-1 -methyl-2,5-cyclohexadiene-4-one-1-carboxylate to afford both enantiomers with 92-96% ee.