PLE catalyzed enantiomeric separation of (+/-)-2-furylcarbinols

Date

1997-01-01

Author

Tanyeli, Cihangir
Arkin, Ali Hakan
Akhmedov, Idris Mecidoğlu

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O-Acetyl derivatives of (+/-)-2-furylcarbinols were resolved by PLE catalyzed hydrolysis to afford optically active 2-furylcarbinols in up to 98% e.e. that are valuable chiral building blocks in the synthesis of various biologically active compounds. Enantiomeric excess values were determined by using H-1-NMR and GC analysis of (S)-O-acetyllactyl ester derivatives of 2-furylcarbinols. They were also correlated with the Literature values.

Subject Keywords

PLE, Enantiomeric Resolution, 2-Furylcarbinols, Biotransformation

URI

https://hdl.handle.net/11511/55683

Journal

ENANTIOMER

Collections

Department of Chemistry, Article

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Citation Formats

C. Tanyeli, A. H. Arkin, and I. M. Akhmedov, “PLE catalyzed enantiomeric separation of (+/-)-2-furylcarbinols,” ENANTIOMER, pp. 433–439, 1997, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/55683.