Quaternized Polymer-Single-Walled Carbon Nanotube Scaffolds for a Chemiresistive Glucose Sensor

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Supporting Information 10.1021:acssensors.7b00323.pdf

Date

2017-08-01

Author

Soylemez, Saniye
Yoon, Bora
Toppare, Levent Kamil
Swager, Timothy M.

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A chemiresistive glucose sensor based on poly(4-vinylpyridine) (P4VP) and single-walled carbon nano tube (SWCNT) composites was reported. To fabricate this glucose sensor, a glass substrate containing gold electrodes was treated with 3-bromopropyltrichlorosilane to obtain a covalent bonding between the polymer SWCNT composite and the glass substrate. Some of the pyridyl moieties in P4VP react with the surface, and the remainders were quaternized using 2-bromoethanol to achieve highly charged hydrophilic surface with improved biocompatibility with enzyme molecules. The resulting biomimetic surface was functionalized with glucose oxidase (GOx) by electrostatic assembly with the quaternized P4VP-SWCNT composite. This material displays a decrease in electrical resistance as a result of enzymatically liberated hydrogen peroxide produced in response to glucose, which increases the p-doping of the SWCNT. The sensor exhibited high selectivity for glucose and showed an instant response (within 3 s) to glucose.

Subject Keywords

Chemiresistive glucose sensor, Single-walled carbon nanotube, Poly(4-vinylpyridine), Quaternization, Glucose oxidase, Glucose detection in beverages

URI

https://hdl.handle.net/11511/38930

Journal

ACS SENSORS

DOI

https://doi.org/10.1021/acssensors.7b00323

Collections

Department of Chemistry, Article

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Citation Formats

S. Soylemez, B. Yoon, L. K. Toppare, and T. M. Swager, “Quaternized Polymer-Single-Walled Carbon Nanotube Scaffolds for a Chemiresistive Glucose Sensor,” ACS SENSORS, pp. 1123–1127, 2017, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/38930.